Mori Fructus improves cognitive and neuronal dysfunction induced by beta-amyloid toxicity through the GSK-3β pathway in vitro and in vivo.-论文-万方医学网

作者： Hyo Geun,Kim ^[1] ; Gunhyuk,Park ^[2] ; Soonmin,Lim ^[2] ; Hanbyeol,Park ^[2] ; Jin Gyu,Choi ^[3] ; Hyun Uk,Jeong ^[3] ; Min Seo,Kang ^[3] ; Mi Kyeong,Lee ^[4] ; Myung Sook,Oh ^[5]

作者单位： College of Pharmacy and Kyung Hee East-West Pharmaceutical Research Institute, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, Republic of Korea; Department of Life and Nanopharmaceutical Science, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, Republic of Korea. ^[1] Department of Life and Nanopharmaceutical Science, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, Republic of Korea. ^[2] College of Pharmacy and Kyung Hee East-West Pharmaceutical Research Institute, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, Republic of Korea. ^[3] College of Pharmacy, Chungbuk National University, Cheongju 361-763, Republic of Korea. ^[4] College of Pharmacy and Kyung Hee East-West Pharmaceutical Research Institute, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, Republic of Korea; Department of Life and Nanopharmaceutical Science, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, Republic of Korea. Electronic address: msohok@khu.ac.kr. ^[5]

主题词阿尔茨海默病(Alzheimer Disease);淀粉样β肽类(Amyloid beta-Peptides);动物(Animals);细胞凋亡(Apoptosis);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);细胞死亡(Cell Death);疾病模型, 动物(Disease Models, Animal);水果(Fruit);糖原合成酶激酶3(Glycogen Synthase Kinase 3);海马(Hippocampus);男(雄)性(Male);膜电位, 线粒体(Membrane Potential, Mitochondrial);小鼠, 近交ICR(Mice, Inbred ICR);桑属(Morus);神经元(Neurons);神经保护药(Neuroprotective Agents);肽碎片(Peptide Fragments);植物药疗法(Phytotherapy);植物提取物(Plant Extracts);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);tau蛋白质类(tau Proteins)

DOI 10.1016/j.jep.2015.05.054

PMID 26068423

发布时间 2016-11-25

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Mori Fructus improves cognitive and neuronal dysfunction induced by beta-amyloid toxicity through the GSK-3β pathway in vitro and in vivo.

Journal of ethnopharmacology

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Mori Fructus improves cognitive and neuronal dysfunction induced by beta-amyloid toxicity through the GSK-3β pathway in vitro and in vivo.

Journal of ethnopharmacology

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Journal of ethnopharmacology

相关期刊

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