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首页> Neuroscience> Exercise prevents downregulation of hippocampal presynaptic proteins following olanzapine-elicited metabolic dysregulation in rats: Distinct roles of inhibitory and excitatory terminals.

Exercise prevents downregulation of hippocampal presynaptic proteins following olanzapine-elicited metabolic dysregulation in rats: Distinct roles of inhibitory and excitatory terminals.

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作者： A,Ramos-Miguel ^[1] ; W G,Honer ^[2] ; H N,Boyda ^[3] ; K,Sawada ^[4] ; C L,Beasley ^[2] ; R M,Procyshyn ^[2] ; A M,Barr ^[3]

作者单位： BC Mental Health & Addictions Research Institute, 938 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada; Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC V6T 2A1, Canada. Electronic address: alfredo.ramos@ubc.ca. ^[1] BC Mental Health & Addictions Research Institute, 938 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada; Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC V6T 2A1, Canada. ^[2] BC Mental Health & Addictions Research Institute, 938 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada; Department of Anesthesiology, Pharmacology, & Therapeutics, University of British Columbia, 2176 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada. ^[3] BC Mental Health & Addictions Research Institute, 938 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada; Kochi Prefectural Aki General Hospital, 1-32 Hoeicho Aki, Kochi Prefecture 784-0027, Japan. ^[4]

关键词 ELISA SNARE atypical antipsychotics confocal microscopy inhibitory terminals metabolic side-effects

主题词动物(Animals);抗精神病药(Antipsychotic Agents);苯二氮|艹卓|类(Benzodiazepines);疾病模型, 动物(Disease Models, Animal);减量调节(Down-Regulation);运动疗法(Exercise Therapy);女(雌)性(Female);海马(Hippocampus);代谢疾病(Metabolic Diseases);神经组织蛋白质类(Nerve Tissue Proteins);R-SNARE蛋白质类(R-SNARE Proteins);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);SNARE蛋白质类(SNARE Proteins)

DOI 10.1016/j.neuroscience.2015.06.022

PMID 26086543

发布时间 2018-12-02

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