换一批DNA hypomethylation-mediated activation of Cancer/Testis Antigen 45 (CT45) genes is associated with disease progression and reduced survival in epithelial ovarian cancer.
第一作者：
Wa,Zhang
第一单位：
a Eppley Institute; University of Nebraska Medical Center ; Omaha , NE USA.
作者：
关键词
CNA, copy number alterationCT antigen genes, cancer-testis or cancer-germline antigen genesCT45DAC, decitabine, 5-Aza-2′-deoxycytidineDFS, disease-free survivalDNA methylationDNMT, DNA methyltransferaseEOC, epithelial ovarian cancerFTE, normal fallopian tube epitheliaHGSOC, high-grade serous ovarian cancerIHC, immunohistochemistryNO, bulk normal ovaryOS, overall survivalOSE, normal ovary surface epitheliaRLM-RACE, 5′ RNA ligase-mediated rapid amplification of cDNA endsRNA-seq, RNA sequencingTCGA, The Cancer Genome AtlasTMA, tissue microarrayTSS, transcription start sitecancer germline genescancer testis antigen genesdecitabineepithelial ovarian cancertumor antigens
医学主题词
老年人(Aged);抗原, 肿瘤(Antigens, Neoplasm);阿扎胞苷(Azacitidine);细胞系, 肿瘤(Cell Line, Tumor);DNA甲基化(DNA Methylation);疾病恶化(Disease Progression);后成说, 遗传(Epigenesis, Genetic);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);中年人(Middle Aged);肿瘤, 腺和上皮(Neoplasms, Glandular and Epithelial);卵巢肿瘤(Ovarian Neoplasms);启动区, 遗传(Promoter Regions, Genetic);RNA, 信使(RNA, Messenger)
DOI
10.1080/15592294.2015.1062206
PMID
26098711
发布时间
2022-03-17
- 浏览106
Epigenetics
736-48页
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