Translocation of gold nanoparticles across the lung epithelial tissue barrier: Combining in vitro and in silico methods to substitute in vivo experiments.

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作者： Gerald,Bachler ^[1] ; Sabrina,Losert ^[2] ; Yuki,Umehara ^[3] ; Natalie,von Goetz ^[4] ; Laura,Rodriguez-Lorenzo ^[5] ; Alke,Petri-Fink ^[6] ; Barbara,Rothen-Rutishauser ^[7] ; Konrad,Hungerbuehler ^[8]

作者单位： ETH Zürich, Institute for Chemical and Bioengineering, 8093, Zürich, Switzerland. gerald.bachler@chem.ethz.ch. ^[1] University of Fribourg, Adolphe Merkle Institute, 1700, Fribourg, Switzerland. gerald.bachler@chem.ethz.ch. ^[2] ETH Zürich, Institute for Chemical and Bioengineering, 8093, Zürich, Switzerland. sabrina.losert@empa.ch. ^[3] EMPA, Swiss Federal Laboratories for Material Science and Technology, 8600, Dübendorf, Switzerland. sabrina.losert@empa.ch. ^[4] University of Fribourg, Adolphe Merkle Institute, 1700, Fribourg, Switzerland. yuki.umehara@unifr.ch. ^[5] ETH Zürich, Institute for Chemical and Bioengineering, 8093, Zürich, Switzerland. natalie.von.goetz@chem.ethz.ch. ^[6] University of Fribourg, Adolphe Merkle Institute, 1700, Fribourg, Switzerland. laura.rodriguez-lorenzo@unifr.ch. ^[7] University of Fribourg, Adolphe Merkle Institute, 1700, Fribourg, Switzerland. alke.fink@unifr.ch. ^[8] University of Fribourg, Adolphe Merkle Institute, 1700, Fribourg, Switzerland. barbara.rothen@unifr.ch. ^[9] ETH Zürich, Institute for Chemical and Bioengineering, 8093, Zürich, Switzerland. konrad.hungerbuehler@chem.ethz.ch. ^[10]

主题词投药, 吸入(Administration, Inhalation);气雾剂(Aerosols);动物(Animals);生物转运(Biological Transport);细胞系, 肿瘤(Cell Line, Tumor);计算机模拟(Computer Simulation);上皮细胞(Epithelial Cells);金化合物(Gold Compounds);人类(Humans);金属纳米粒子(Metal Nanoparticles);小鼠(Mice);模型, 生物学(Models, Biological);粒子大小(Particle Size);呼吸道黏膜(Respiratory Mucosa);组织分布(Tissue Distribution)

DOI 10.1186/s12989-015-0090-8

PMID 26116549

发布时间 2022-03-17

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Particle and fibre toxicology

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Translocation of gold nanoparticles across the lung epithelial tissue barrier: Combining in vitro and in silico methods to substitute in vivo experiments.

Particle and fibre toxicology

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Translocation of gold nanoparticles across the lung epithelial tissue barrier: Combining in vitro and in silico methods to substitute in vivo experiments.

Particle and fibre toxicology

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Particle and fibre toxicology

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