Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates.-论文-万方医学网

第一作者： Daniel F,Egan

第一单位： Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

作者： Daniel F,Egan ^[1] ; Matthew G H,Chun ^[1] ; Mitchell,Vamos ^[2] ; Haixia,Zou ^[2] ; Juan,Rong ^[2] ; Chad J,Miller ^[3] ; Hua Jane,Lou ^[3] ; Dhanya,Raveendra-Panickar ^[2] ; Chih-Cheng,Yang ^[4] ; Douglas J,Sheffler ^[2] ; Peter,Teriete ^[2] ; John M,Asara ^[5] ; Benjamin E,Turk ^[3] ; Nicholas D P,Cosford ^[6] ; Reuben J,Shaw ^[7]

作者单位： Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. ^[1] Cell Death and Survival Networks Research Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. ^[2] Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA. ^[3] Functional Genomics Core, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. ^[4] Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA. ^[5] Cell Death and Survival Networks Research Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address: ncosford@sanfordburnham.org. ^[6] Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address: shaw@salk.edu. ^[7]

主题词氨基酸序列(Amino Acid Sequence);动物(Animals);自噬(Autophagy);苯甲酰胺类(Benzamides);催化域(Catalytic Domain);细胞存活(Cell Survival);细胞, 培养的(Cells, Cultured);共有序列(Consensus Sequence);基因敲除技术(Gene Knockout Techniques);HEK293细胞(HEK293 Cells);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);小鼠(Mice);分子序列数据(Molecular Sequence Data);磷酰化(Phosphorylation);蛋白激酶抑制剂(Protein Kinase Inhibitors);嘧啶类(Pyrimidines);RNA, 小分子干扰(RNA, Small Interfering);重组蛋白质类(Recombinant Proteins);底物特异性(Substrate Specificity)

DOI 10.1016/j.molcel.2015.05.031

PMID 26118643

发布时间 2022-04-08

检索历史清除

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates.

Molecular cell

相似文献

Molecular cell

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates.

Molecular cell

相似文献

Molecular cell

相关期刊

检索历史清除