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ELQ-300 prodrugs for enhanced delivery and single-dose cure of malaria.

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第一作者： Galen P,Miley

第一单位： VA Medical Center, Experimental Chemotherapy Laboratory, Portland, Oregon, USA.

作者： Galen P,Miley ^[1] ; Sovitj,Pou ^[1] ; Rolf,Winter ^[1] ; Aaron,Nilsen ^[1] ; Yuexin,Li ^[1] ; Jane X,Kelly ^[1] ; Allison M,Stickles ^[2] ; Michael W,Mather ^[3] ; Isaac P,Forquer ^[1] ; April M,Pershing ^[3] ; Karen,White ^[4] ; David,Shackleford ^[4] ; Jessica,Saunders ^[4] ; Gong,Chen ^[4] ; Li-Min,Ting ^[5] ; Kami,Kim ^[5] ; Lev N,Zakharov ^[6] ; Cristina,Donini ^[7] ; Jeremy N,Burrows ^[7] ; Akhil B,Vaidya ^[8] ; Susan A,Charman ^[9] ; Michael K,Riscoe ^[10]

作者单位： VA Medical Center, Experimental Chemotherapy Laboratory, Portland, Oregon, USA. ^[1] Oregon Health & Science University, Department of Molecular Microbiology and Immunology, Portland, Oregon, USA. ^[2] Drexel University College of Medicine, Department of Microbiology and Immunology, Philadelphia, Pennsylvania, USA. ^[3] Monash University, Centre for Drug Candidate Optimization, Parkville, Australia. ^[4] Albert Einstein College of Medicine, Departments of Medicine, Pathology, and Microbiology and Immunology, Bronx, New York, USA. ^[5] CAMCOR, University of Oregon, Eugene, Oregon, USA. ^[6] Medicines for Malaria Venture, Geneva, Switzerland. ^[7] Drexel University College of Medicine, Department of Microbiology and Immunology, Philadelphia, Pennsylvania, USA Akhil.Vaidya@DrexelMed.edu Susan.Charman@monash.edu riscoem@ohsu.edu. ^[8] Monash University, Centre for Drug Candidate Optimization, Parkville, Australia Akhil.Vaidya@DrexelMed.edu Susan.Charman@monash.edu riscoem@ohsu.edu. ^[9] VA Medical Center, Experimental Chemotherapy Laboratory, Portland, Oregon, USA Oregon Health & Science University, Department of Molecular Microbiology and Immunology, Portland, Oregon, USA Akhil.Vaidya@DrexelMed.edu Susan.Charman@monash.edu riscoem@ohsu.edu. ^[10]