A role for the thermal environment in defining co-stimulation requirements for CD4(+) T cell activation.
第一作者:
Evan R,Zynda
第一单位:
a Department of Cell Stress Biology ; Roswell Park Cancer Institute ; Buffalo , NY USA.
作者:
关键词
APC, antigen-presenting cellCD28, cluster of differentiation 28CD3, cluster of differentiation 3CD4, cluster of differentiation 4CD8, cluster of differentiation 8CTLA-4, cytotoxic T-lymphocyte-associated protein 4CTxB, cholera toxin B subunitCt, cycle thresholdELISA, enzyme-linked immunosorbant assayEtOH, ethanolFITC, fluoroisothiocyanateGM1, monosialotetrahexosylgangliosideIDEAS, imagestream data exploration and analysis softwareIL-2, interleukin 2LA, latrunculin AMβCD, methyl-β-cyclodextrinPD-1, Programmed cell death-1PMA, phorbol 12-myristate 13-acetateT cell activationT cell co-stimulationTCR, T cell receptorTDI, time delay integrationTMA-DPH, trimethylammonium diphenylhexatrieneWBH, whole body hyperthermia.feverhyperthermiaimmune responsemembrane fluiditypMHC, peptide-major histocompatibility complexesqRT-PCR, quantitative reverse transcription polymerase chain reaction
医学主题词
动物(Animals);锚蛋白类(Ankyrins);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);荧光偏振(Fluorescence Polarization);人类(Humans);白细胞介素2(Interleukin-2);Jurkat细胞(Jurkat Cells);淋巴细胞活化(Lymphocyte Activation);膜流动性(Membrane Fluidity);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 基因敲除(Mice, Knockout);RNA, 信使(RNA, Messenger);膜收缩蛋白(Spectrin);温度(Temperature);十四酰佛波乙酯(Tetradecanoylphorbol Acetate);β环糊精类(beta-Cyclodextrins)
DOI
10.1080/15384101.2015.1049782
PMID
26131730
发布时间
2020-09-30
- 浏览19
Cell cycle (Georgetown, Tex.)
2340-54页
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