The angiotensin receptor blocker losartan reduces coronary arteriole remodeling in type 2 diabetic mice.

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作者： Kathryn E,Husarek ^[1] ; Paige S,Katz ^[2] ; Aaron J,Trask ^[3] ; Maarten L,Galantowicz ^[4] ; Mary J,Cismowski ^[4] ; Pamela A,Lucchesi ^[5]

作者单位： Center for Cardiovascular and Pulmonary Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH, United States; School of Biomedical Science, The Ohio State University College of Medicine, Columbus, OH, United States. ^[1] Center for Cardiovascular and Pulmonary Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH, United States; Department of Physiology, Louisiana State University Health Sciences Center, New Orleans, LA, United States. ^[2] Center for Cardiovascular and Pulmonary Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH, United States; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, United States. ^[3] Center for Cardiovascular and Pulmonary Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH, United States. ^[4] Center for Cardiovascular and Pulmonary Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH, United States; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, United States. Electronic address: Pamela.Lucchesi@nationwidechildrens.org. ^[5]

关键词 Angiotensin receptor blocker Coronary arterioles Type 2 diabetes mellitus Vascular remodeling