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Characterization of myeloid leukocytes and soluble mediators in pancreatic cancer: importance of myeloid-derived suppressor cells.

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第一作者： Svetlana,Karakhanova

第一单位： Department of General Surgery; University of Heidelberg ; Heidelberg, Germany.

作者： Svetlana,Karakhanova ^[1] ; Julia,Link ^[1] ; Moritz,Heinrich ^[1] ; Ivan,Shevchenko ^[2] ; Yuhui,Yang ^[3] ; Matthias,Hassenpflug ^[1] ; Henriette,Bunge ^[1] ; Katharina,von Ahn ^[1] ; Ramona,Brecht ^[1] ; Andreas,Mathes ^[1] ; Caroline,Maier ^[1] ; Viktor,Umansky ^[4] ; Jens,Werner ^[5] ; Alexandr V,Bazhin ^[5]

作者单位： Department of General Surgery; University of Heidelberg ; Heidelberg, Germany. ^[1] Department of General Surgery; University of Heidelberg ; Heidelberg, Germany ; Skin Cancer Unit; German Cancer Research Center (DKFZ) ; Heidelberg and Department of Dermatology; Venereology and Allergology ; University Medical Center Mannheim; University of Heidelberg ; Heidelberg, Germany. ^[2] Department of General Surgery; University of Heidelberg ; Heidelberg, Germany ; Cancer Center; Union Hospital ; Tongji Medical College; Huazhong University of Science and Technology ; Wuhan, China. ^[3] Skin Cancer Unit; German Cancer Research Center (DKFZ) ; Heidelberg and Department of Dermatology; Venereology and Allergology ; University Medical Center Mannheim; University of Heidelberg ; Heidelberg, Germany. ^[4] Department of General; Visceral, and Transplant Surgery ; Ludwig-Maximilians-University Munich ; Germany. ^[5]

关键词 ARG-1, arginase-1 DC, dendritic cells MDSC MDSC, myeloid-derived suppressor cells NO, nitric oxide PDAC, pancreatic ductal adenocarcinoma TIL, tumor-infiltrating leukocytes Tregs, regulatory T cells immune suppression orthotopic Panc02 model pancreatic adenocarcinoma

DOI 10.1080/2162402X.2014.998519

PMID 26137414

发布时间 2021-01-12

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