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Clinical Validation of a Multiplex Kit for RAS Mutations in Colorectal Cancer: Results of the RASKET (RAS KEy Testing) Prospective, Multicenter Study.

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第一作者： Takayuki,Yoshino

第一单位： Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, Japan.

作者： Takayuki,Yoshino ^[1] ; Kei,Muro ^[2] ; Kensei,Yamaguchi ^[3] ; Tomohiro,Nishina ^[4] ; Tadamichi,Denda ^[5] ; Toshihiro,Kudo ^[6] ; Wataru,Okamoto ^[7] ; Hiroya,Taniguchi ^[2] ; Kiwamu,Akagi ^[8] ; Takeshi,Kajiwara ^[4] ; Shuichi,Hironaka ^[9] ; Taroh,Satoh ^[6]

作者单位： Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, Japan. ^[1] Department of Clinical Oncology, Aichi Cancer Center Hospital, Aichi, Japan. ^[2] Division of Gastroenterology, Saitama Cancer Center, Saitama, Japan. ^[3] Department of Gastrointestinal Medical Oncology, National Hospital Organization Shikoku Cancer Center, Ehime, Japan. ^[4] Division of Gastroenterology, Chiba Cancer Center, Chiba, Japan. ^[5] Department of Frontier Science for Cancer and Chemotherapy, Osaka University Graduate School of Medicine, Osaka, Japan. ^[6] Division of Translational Research, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Chiba, Japan. ^[7] Division of Molecular Diagnosis and Cancer Prevention, Saitama Cancer Center, Saitama, Japan. ^[8] Clinical Trial Promotion Department, Chiba Cancer Center, Chiba, Japan. ^[9]

关键词 Anti-EGFR antibody treatment Biomarker Colorectal cancer In vitro diagnostics RAS mutation RASKET study