pHLIP-mediated targeting of truncated tissue factor to tumor vessels causes vascular occlusion and impairs tumor growth.-论文-万方医学网

作者： Suping,Li ^[1] ; Yanhua,Tian ^[2] ; Ying,Zhao ^[1] ; Yinlong,Zhang ^[1] ; Shishuai,Su ^[1] ; Jing,Wang ^[1] ; Meiyu,Wu ^[1] ; Quanwei,Shi ^[1] ; Gregory J,Anderson ^[3] ; Johannes,Thomsen ^[4] ; Ruifang,Zhao ^[1] ; Tianjiao,Ji ^[1] ; Jie,Wang ^[5] ; Guangjun,Nie ^[1]

作者单位： CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology, China, Beijing 100190, China. ^[1] Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China. ^[2] QIMR Berghofer Medical Research Institute, Brisbane QLD 4006, Australia. ^[3] Sino-Danish Center for Education and Research, University of Chinese Academy of Sciences, Beijing 100190, China. ^[4] Department of Thoracic Medical Oncology, Peking University Cancer Hospital and Institute, Beijing 100142, China. ^[5]

主题词动物(Animals);抗肿瘤药(Antineoplastic Agents);血液凝固(Blood Coagulation);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞膜(Cell Membrane);因子Ⅹ(Factor X);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);脂双层(Lipid Bilayers);黑色素瘤, 实验性(Melanoma, Experimental);膜蛋白质类(Membrane Proteins);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);肿瘤移植(Neoplasm Transplantation);新生血管化, 病理性(Neovascularization, Pathologic);灌流(Perfusion);蛋白质结构, 三级(Protein Structure, Tertiary);凝血致活酶(Thromboplastin);血栓形成(Thrombosis)

DOI 10.18632/oncotarget.4395

PMID 26143637

发布时间 2024-03-24

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pHLIP-mediated targeting of truncated tissue factor to tumor vessels causes vascular occlusion and impairs tumor growth.

Oncotarget

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pHLIP-mediated targeting of truncated tissue factor to tumor vessels causes vascular occlusion and impairs tumor growth.

Oncotarget

相似文献

Oncotarget

相关期刊

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