Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis.

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第一作者： Chuanyue,Wu

第一单位： 1] Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA. [2] Department of Biology and Shenzhen Key Laboratory of Cell Microenvironment, South University of Science and Technology of China, Shenzhen 518055, China.

作者： Chuanyue,Wu ^[1] ; Hongli,Jiao ^[2] ; Yumei,Lai ^[2] ; Wei,Zheng ^[2] ; Ka,Chen ^[3] ; Hong,Qu ^[3] ; Weimin,Deng ^[2] ; Pingping,Song ^[2] ; Ke,Zhu ^[2] ; Huiling,Cao ^[4] ; Deborah L,Galson ^[5] ; Jie,Fan ^[6] ; Hee-Jeong,Im ^[2] ; Yujie,Liu ^[7] ; Ju,Chen ^[7] ; Di,Chen ^[2] ; Guozhi,Xiao ^[8]

作者单位： 1] Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA. [2] Department of Biology and Shenzhen Key Laboratory of Cell Microenvironment, South University of Science and Technology of China, Shenzhen 518055, China. ^[1] Department of Biochemistry, Rush University Medical Center, Chicago, Illinois 60612, USA. ^[2] Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA. ^[3] Department of Biology and Shenzhen Key Laboratory of Cell Microenvironment, South University of Science and Technology of China, Shenzhen 518055, China. ^[4] Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15240, USA. ^[5] Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15240, USA. ^[6] Department of Medicine, University of California San Diego, La Jolla, California 92093, USA. ^[7] 1] Department of Biology and Shenzhen Key Laboratory of Cell Microenvironment, South University of Science and Technology of China, Shenzhen 518055, China. [2] Department of Biochemistry, Rush University Medical Center, Chicago, Illinois 60612, USA. ^[8]

主题词动物(Animals);动物, 新生(Animals, Newborn);软骨细胞(Chondrocytes);软骨发生(Chondrogenesis);细胞支架蛋白质类(Cytoskeletal Proteins);胚胎, 哺乳动物(Embryo, Mammalian);基因表达调控, 发育期(Gene Expression Regulation, Developmental);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);肌蛋白质类(Muscle Proteins);SOX9转录因子类(SOX9 Transcription Factor);信号传导(Signal Transduction);骨骼(Skeleton);转化生长因子β(Transforming Growth Factor beta)

DOI 10.1038/ncomms8531

PMID 26151572

发布时间 2018-11-13

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Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis.

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Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis.

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