The genetic variant rs4073 A→T of the Interleukin-8 promoter region is associated with the earlier onset of exudative age-related macular degeneration.
第一作者:
Asta,Hautamäki
第一单位:
Department of Ophthalmology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
作者:
医学主题词
老年人(Aged);老年人, 80以上(Aged, 80 and over);补体C3(Complement C3);补体因子H(Complement Factor H);女(雌)性(Female);基因型(Genotype);地图样萎缩(Geographic Atrophy);人类(Humans);白细胞介素8(Interleukin-8);男(雄)性(Male);中年人(Middle Aged);聚合酶链反应(Polymerase Chain Reaction);多态性, 单核苷酸(Polymorphism, Single Nucleotide);启动区, 遗传(Promoter Regions, Genetic);回顾性研究(Retrospective Studies);危险因素(Risk Factors);吸烟(Smoking);湿性黄斑变性(Wet Macular Degeneration)
DOI
10.1111/aos.12799
PMID
26154559
发布时间
2021-05-14
- 浏览31
Acta ophthalmologica
726-33页
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