Erk regulation of actin capping and bundling by Eps8 promotes cortex tension and leader bleb-based migration.

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作者： Jeremy S,Logue ^[1] ; Alexander X,Cartagena-Rivera ^[2] ; Michelle A,Baird ^[1] ; Michael W,Davidson ^[3] ; Richard S,Chadwick ^[2] ; Clare M,Waterman ^[1]

作者单位： National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, United States. ^[1] National Institute on Deafness and other Communication Disorders, National Institutes of Health, Bethesda, United States. ^[2] National High Magnetic Field Laboratory and Department of Biological Science, Florida State University, Tallahassee, United States. ^[3]

关键词 Eps8 Erk actin adhesion-independent cell migration bleb cancer cell biology cell biology human

主题词肌动蛋白类(Actins);衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);人类(Humans)

DOI 10.7554/eLife.08314

PMID 26163656

发布时间 2018-11-13

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