Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.

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作者： Giles W,Robinson ^[1] ; Brent A,Orr ^[2] ; Gang,Wu ^[2] ; Sridharan,Gururangan ^[2] ; Tong,Lin ^[2] ; Ibrahim,Qaddoumi ^[2] ; Roger J,Packer ^[2] ; Stewart,Goldman ^[2] ; Michael D,Prados ^[2] ; Annick,Desjardins ^[2] ; Murali,Chintagumpala ^[2] ; Naoko,Takebe ^[2] ; Sue C,Kaste ^[2] ; Michael,Rusch ^[2] ; Sariah J,Allen ^[2] ; Arzu,Onar-Thomas ^[2] ; Clinton F,Stewart ^[2] ; Maryam,Fouladi ^[2] ; James M,Boyett ^[2] ; Richard J,Gilbertson ^[2] ; Tom,Curran ^[2] ; David W,Ellison ^[2] ; Amar,Gajjar ^[2]

作者单位： Giles W. Robinson, Brent A. Orr, Gang Wu, Tong Lin, Ibrahim Qaddoumi, Sue C. Kaste, Michael Rusch, Sariah J. Allen, Arzu Onar-Thomas, Clinton F. Stewart, James M. Boyett, Richard J. Gilbertson, David W. Ellison, and Amar Gajjar, St Jude Children's Research Hospital, Memphis, TN; Sridharan Gururangan and Annick Desjardins, Duke University Medical Center, Durham, NC; Roger J. Packer, Children's National Medical Center, Washington, DC; Stewart Goldman, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Michael D. Prados, University of California San Francisco, San Francisco, CA; Murali Chintagumpala, Texas Children's Cancer Center, Houston, TX; Naoko Takebe, National Cancer Institute, Bethesda, MD; Maryam Fouladi, Cincinnati Children's Hospital, Cincinnati, OH; and Tom Curran, Children's Hospital of Philadelphia, Philadelphia, PA. giles.robinson@stjude.org. ^[1] Giles W. Robinson, Brent A. Orr, Gang Wu, Tong Lin, Ibrahim Qaddoumi, Sue C. Kaste, Michael Rusch, Sariah J. Allen, Arzu Onar-Thomas, Clinton F. Stewart, James M. Boyett, Richard J. Gilbertson, David W. Ellison, and Amar Gajjar, St Jude Children's Research Hospital, Memphis, TN; Sridharan Gururangan and Annick Desjardins, Duke University Medical Center, Durham, NC; Roger J. Packer, Children's National Medical Center, Washington, DC; Stewart Goldman, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Michael D. Prados, University of California San Francisco, San Francisco, CA; Murali Chintagumpala, Texas Children's Cancer Center, Houston, TX; Naoko Takebe, National Cancer Institute, Bethesda, MD; Maryam Fouladi, Cincinnati Children's Hospital, Cincinnati, OH; and Tom Curran, Children's Hospital of Philadelphia, Philadelphia, PA. ^[2]