Microbes & neurodevelopment--Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala.

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作者： Roman M,Stilling ^[1] ; Feargal J,Ryan ^[2] ; Alan E,Hoban ^[1] ; Fergus,Shanahan ^[3] ; Gerard,Clarke ^[4] ; Marcus J,Claesson ^[2] ; Timothy G,Dinan ^[4] ; John F,Cryan ^[5]

作者单位： APC Microbiome Institute, University College Cork, Cork, Ireland; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland. ^[1] APC Microbiome Institute, University College Cork, Cork, Ireland; Department of Microbiology, University College Cork, Cork, Ireland. ^[2] APC Microbiome Institute, University College Cork, Cork, Ireland. ^[3] APC Microbiome Institute, University College Cork, Cork, Ireland; Department of Psychiatry and Neurobehavioural Sciences, University College Cork, Ireland. ^[4] APC Microbiome Institute, University College Cork, Cork, Ireland; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland. Electronic address: j.cryan@ucc.ie. ^[5]

关键词 Activity-induced Differential gene expression Gene regulation Gut–brain axis Hyper-excitability Immediate early gene MAP-kinase pathway Microbiome RNA editing RNA-seq