How individual participant data meta-analyses have influenced trial design, conduct, and analysis.

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作者： Jayne F,Tierney ^[1] ; Jean-Pierre,Pignon ^[2] ; Francois,Gueffyier ^[3] ; Mike,Clarke ^[4] ; Lisa,Askie ^[5] ; Claire L,Vale ^[6] ; Sarah,Burdett ^[6] ; Cochrane IPD Meta-analysis Methods Group

作者单位： MRC Clinical Trials Unit at UCL, Aviation House, 125 Kingsway, London WC2B 6NH, UK. Electronic address: jayne.tierney@ucl.ac.uk. ^[1] LNCC plateforme de méta-analyse en oncologie, Service de Biostatistique et d'Epidemiologie, Gustave-Roussy, Villejuif, France. ^[2] Université Claude Bernard Lyon 1/Université de Lyon, 69365 Lyon Cedex 07, Lyon, France; Service de Pharmacologie Clinique, Hospices Civils de Lyon, Bron cedex, France. ^[3] All-Ireland Hub for Trials Methodology Research, Queen's University Belfast, University Road, Belfast BT7 1NN, Northern Ireland, UK. ^[4] NHMRC Clinical Trials Centre, ABN 15 211 513 464, Locked Bag 77, Camperdown, NSW 1450 Australia. ^[5] MRC Clinical Trials Unit at UCL, Aviation House, 125 Kingsway, London WC2B 6NH, UK. ^[6]

关键词 Individual participant data (IPD)Meta-analysis Systematic review Trial analysis Trial conduct Trial design

主题词临床试验(主题)(Clinical Trials as Topic);人类(Humans);Meta分析(主题)(Meta-Analysis as Topic);研究设计(Research Design);研究对象(Research Subjects);统计学(主题)(Statistics as Topic)

DOI 10.1016/j.jclinepi.2015.05.024

PMID 26186982

发布时间 2021-01-09

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