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Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation.

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第一作者: Jeong-Hwan,Yoon
第一单位: 1] Department of Experimental Pathology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan [2] Department of Molecular Pathology, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan [3] Department of Internal Medicine, Kyungpook National University School of Medicine, 50 SAMDUK-2GA, Jungu, Daegu 700-721, Republic of Korea.
作者单位: 1] Department of Experimental Pathology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan [2] Department of Molecular Pathology, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan [3] Department of Internal Medicine, Kyungpook National University School of Medicine, 50 SAMDUK-2GA, Jungu, Daegu 700-721, Republic of Korea. [1] Animal Research Center, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan. [2] Department of Molecular Pathology, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan. [3] Department of Experimental Pathology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan. [4] Department of Internal Medicine, Kyungpook National University School of Medicine, 50 SAMDUK-2GA, Jungu, Daegu 700-721, Republic of Korea. [5] Department of Laboratory Animal Medicine, Institute for the 3Rs, College of Veterinary Medicine, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 143-701, Republic of Korea. [6] Laboratory of Systems Biology, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato, Tokyo 108-8639, Japan. [7] Department of Molecular Medicine for Pathogenesis, Graduate School of Medicine, Ehime University, Shitsukawa, Toon, Ehime 791-0295, Japan. [8] Department of Rheumatology, Catholic University of Korea, #505, Banpo-Dong, Seocho-Gu, Seoul 137-701, Republic of Korea. [9] College of Pharmacy, Ewha Womans University, 11-1 Daehyun-dong, Seodaemun-gu, Seoul 120-750, Republic of Korea. [10] Department of Gastroenterology and Hepatology, Kansai Medical University, 10-15 Fumizonocho, Moriguchi, Osaka 570-8506, Japan. [11] Department of Molecular Genetics, Ohio State University, 484 West 12th Avenue, Columbus, Ohio 43210, USA. [12] Department of Internal Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan. [13] 1] Department of Molecular Pathology, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan [2] Department of Internal Medicine, Kyungpook National University School of Medicine, 50 SAMDUK-2GA, Jungu, Daegu 700-721, Republic of Korea. [14]
DOI 10.1038/ncomms8600
PMID 26194464
发布时间 2018-11-13
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