Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.-论文-万方医学网

作者： Michael,Thiele ^[1] ; Randolf J,Kerschbaumer ^[2] ; Frederick W K,Tam ^[3] ; Dirk,Völkel ^[1] ; Patrice,Douillard ^[1] ; Alexander,Schinagl ^[1] ; Harald,Kühnel ^[1] ; Jennifer,Smith ^[3] ; John P,McDaid ^[3] ; Gurjeet,Bhangal ^[3] ; Mei-Ching,Yu ^[3] ; Charles D,Pusey ^[3] ; H Terence,Cook ^[3] ; Josef,Kovarik ^[4] ; Erica,Magelky ^[5] ; Atul,Bhan ^[6] ; Manfred,Rieger ^[1] ; Geert C,Mudde ^[1] ; Hartmut,Ehrlich ^[1] ; Bernd,Jilma ^[7] ; Herbert,Tilg ^[8] ; Alexander,Moschen ^[8] ; Cox,Terhorst ^[5] ; Friedrich,Scheiflinger ^[1]

作者单位： Baxter Biomedical Research Center, Baxter Innovations GmbH, 2304 Orth/Donau, Austria; ^[1] Baxter Biomedical Research Center, Baxter Innovations GmbH, 2304 Orth/Donau, Austria; randolf_kerschbaumer@baxter.com. ^[2] Imperial College Renal and Transplant Centre, Hammersmith Hospital, London W12 0NN, United Kingdom; ^[3] Department of Nephrology, Wilhelminenspital, 1160 Vienna, Austria; ^[4] Department of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215; ^[5] Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02214; ^[6] Department of Clinical Pharmacology, Medical University Vienna, 1090 Vienna, Austria; and. ^[7] Department of Internal Medicine I, Endocrinology, Gastroenterology & Metabolism, Medical University Innsbruck, 6020 Innsbruck, Austria. ^[8]

主题词动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);印迹法, 蛋白质(Blotting, Western);地塞米松(Dexamethasone);疾病模型, 动物(Disease Models, Animal);小肠结肠炎(Enterocolitis);流式细胞术(Flow Cytometry);肾小球肾炎(Glomerulonephritis);糖皮质激素类(Glucocorticoids);人类(Humans);炎症(Inflammation);巨噬细胞游走抑制因子(Macrophage Migration-Inhibitory Factors);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);分子靶向治疗(Molecular Targeted Therapy);氧化还原(Oxidation-Reduction);蛋白质构象(Protein Conformation);蛋白质亚型(Protein Isoforms);兔(Rabbits);大鼠, 近交WKY(Rats, Inbred WKY)

DOI 10.4049/jimmunol.1500572

PMID 26209628

发布时间 2021-04-09

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Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.

Journal of immunology (Baltimore, Md.

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Journal of immunology (Baltimore, Md.

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Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.

Journal of immunology (Baltimore, Md.

相似文献

Journal of immunology (Baltimore, Md.

相关期刊

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