MRP4 Modulation of the Guanylate Cyclase-C/cGMP Pathway: Effects on Linaclotide-Induced Electrolyte Secretion and cGMP Efflux.
第一作者:
Boris,Tchernychev
第一单位:
Ironwood Pharmaceuticals, Cambridge, Massachusetts (B.T., P.G., M.M.K., R.M.S., D.W., J.V.T., A.F., G.H., A.P.B., C.B.K., M.G.C., I.S.-S.); and Ralph N. Adams Institute for Bioanalytical Chemistry, Department of Chemistry, University of Kansas, Lawrence, Kansas (S.R.T., C.E.L.).
作者:
医学主题词
动物(Animals);生物转运(Biological Transport);结肠(Colon);环GMP(Cyclic GMP);电解质(Electrolytes);电生理学现象(Electrophysiological Phenomena);女(雌)性(Female);肠黏膜(Intestinal Mucosa);动力学(Kinetics);多药耐药相关蛋白质类(Multidrug Resistance-Associated Proteins);肽类(Peptides);丙酸盐类(Propionates);喹啉类(Quinolines);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);受体, 鸟苷酸环化酶偶联(Receptors, Guanylate Cyclase-Coupled);受体, 肽(Receptors, Peptide);信号传导(Signal Transduction)
DOI
10.1124/jpet.115.224329
PMID
26216942
发布时间
2025-03-06
- 浏览36
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文


换一批



