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Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor.

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第一作者： William D,Tap

第一单位： From Memorial Sloan Kettering Cancer Center (W.D.T., J.H.H.) and Weill Cornell Medical College (W.D.T.) - both in New York; University of California, Los Angeles, Medical Center, Los Angeles (Z.A.W., B.C., A.S.S.), Plexxikon, Berkeley (P.N.I., C.Z., J.Z., G.H., Y.Z., E.A.B., G.V., L.S., P.S., H.N., M.J.K., A.M., G.T., R.S., C.G., B.L.W., P.H., K.N., H.H.H., P.S.L., S.T.-S., G.B.), and Stanford University School of Medicine, Stanford (M.R.) - all in California; Evergreen Hematology and Oncology, Spokane, WA (S.P.A.); University of Pennsylvania School of Medicine, Philadelphia (A.P.S.); Rocky Mountain Cancer Centers, Denver (A.L.C.); Dana-Farber Cancer Institute (G.I.S., A.J.W.) and Massachusetts General Hospital (E.L.K.) - both in Boston; Vanderbilt University Medical Center, Nashville (V.L.K., I.P.); Virginia G. Piper Cancer Center at Scottsdale Healthcare-Translational Genomics Research Institute (TGen), Scottsdale, AZ (D.D.V.H., G.J.W., R.K.R.); and Spire Sciences, Boca Raton, FL (C.P.).

作者： William D,Tap ^[1] ; Zev A,Wainberg ; Stephen P,Anthony ; Prabha N,Ibrahim ; Chao,Zhang ; John H,Healey ; Bartosz,Chmielowski ; Arthur P,Staddon ; Allen Lee,Cohn ; Geoffrey I,Shapiro ; Vicki L,Keedy ; Arun S,Singh ; Igor,Puzanov ; Eunice L,Kwak ; Andrew J,Wagner ; Daniel D,Von Hoff ; Glen J,Weiss ; Ramesh K,Ramanathan ; Jiazhong,Zhang ; Gaston,Habets ; Ying,Zhang ; Elizabeth A,Burton ; Gary,Visor ; Laura,Sanftner ; Paul,Severson ; Hoa,Nguyen ; Marie J,Kim ; Adhirai,Marimuthu ; Garson,Tsang ; Rafe,Shellooe ; Carolyn,Gee ; Brian L,West ; Peter,Hirth ; Keith,Nolop ; Matt,van de Rijn ; Henry H,Hsu ; Charles,Peterfy ; Paul S,Lin ; Sandra,Tong-Starksen ; Gideon,Bollag

作者单位： From Memorial Sloan Kettering Cancer Center (W.D.T., J.H.H.) and Weill Cornell Medical College (W.D.T.) - both in New York; University of California, Los Angeles, Medical Center, Los Angeles (Z.A.W., B.C., A.S.S.), Plexxikon, Berkeley (P.N.I., C.Z., J.Z., G.H., Y.Z., E.A.B., G.V., L.S., P.S., H.N., M.J.K., A.M., G.T., R.S., C.G., B.L.W., P.H., K.N., H.H.H., P.S.L., S.T.-S., G.B.), and Stanford University School of Medicine, Stanford (M.R.) - all in California; Evergreen Hematology and Oncology, Spokane, WA (S.P.A.); University of Pennsylvania School of Medicine, Philadelphia (A.P.S.); Rocky Mountain Cancer Centers, Denver (A.L.C.); Dana-Farber Cancer Institute (G.I.S., A.J.W.) and Massachusetts General Hospital (E.L.K.) - both in Boston; Vanderbilt University Medical Center, Nashville (V.L.K., I.P.); Virginia G. Piper Cancer Center at Scottsdale Healthcare-Translational Genomics Research Institute (TGen), Scottsdale, AZ (D.D.V.H., G.J.W., R.K.R.); and Spire Sciences, Boca Raton, FL (C.P.). ^[1]