GBM Derived Gangliosides Induce T Cell Apoptosis through Activation of the Caspase Cascade Involving Both the Extrinsic and the Intrinsic Pathway.
作者:
主题词
细胞凋亡(Apoptosis);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞系, 肿瘤(Cell Line, Tumor);G(M2)神经节苷脂(G(M2) Ganglioside);基因敲除技术(Gene Knockout Techniques);胶质母细胞瘤(Glioblastoma);人类(Humans);免疫沉淀法(Immunoprecipitation);Jurkat细胞(Jurkat Cells);显微镜检查, 共焦(Microscopy, Confocal);活性氧(Reactive Oxygen Species);受体, 肿瘤坏死因子(Receptors, Tumor Necrosis Factor);信号传导(Signal Transduction);T淋巴细胞(T-Lymphocytes)
DOI
10.1371/journal.pone.0134425
PMID
26226135
发布时间
2020-12-15
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PloS one
e0134425页
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