Exclusive Transduction of Human CD4+ T Cells upon Systemic Delivery of CD4-Targeted Lentiviral Vectors.-论文-万方医学网

第一作者： Qi,Zhou

第一单位： Molecular Biotechnology and Gene Therapy, Paul-Ehrlich-Institut, 63225 Langen, Germany;

作者： Qi,Zhou ^[1] ; Katharina M,Uhlig ^[1] ; Anke,Muth ^[1] ; Janine,Kimpel ^[2] ; Camille,Lévy ^[3] ; Robert C,Münch ^[1] ; Janna,Seifried ^[4] ; Anett,Pfeiffer ^[1] ; Alexandra,Trkola ^[5] ; Cheick,Coulibaly ^[6] ; Dorothee,von Laer ^[2] ; Winfried S,Wels ^[7] ; Udo F,Hartwig ^[8] ; Els,Verhoeyen ^[9] ; Christian J,Buchholz ^[10]

作者单位： Molecular Biotechnology and Gene Therapy, Paul-Ehrlich-Institut, 63225 Langen, Germany; ^[1] Division of Virology, Medical University of Innsbruck, A-6020 Innsbruck, Austria; ^[2] Centre International de Recherche en Infectiologie, Virus Enveloppés, Vecteurs et Réponses Innées Équipe, INSERM U1111, Centre National de la Recherche Scientifique, Unités Mixtes de Recherche 5308, Université de Lyon-1, École Normale Supérieure de Lyon, 69007 Lyon, France; ^[3] Host Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany; ^[4] Institute of Medical Virology, University of Zurich, CH-8057 Zurich, Switzerland; ^[5] Central Animal Unit, Paul-Ehrlich-Institut, 63225 Langen, Germany; ^[6] Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, D-60596 Frankfurt, Germany; ^[7] 3rd Department of Medicine-Hematology, Internal Oncology and Pneumology, University Medical Center of Johannes Gutenberg-University Mainz, 55131 Mainz, Germany; ^[8] Centre International de Recherche en Infectiologie, Virus Enveloppés, Vecteurs et Réponses Innées Équipe, INSERM U1111, Centre National de la Recherche Scientifique, Unités Mixtes de Recherche 5308, Université de Lyon-1, École Normale Supérieure de Lyon, 69007 Lyon, France; INSERM U1065, Centre Méditerranéen de Médecine Moléculaire, Équipe 3, 06204 Nice, France; and. ^[9] Molecular Biotechnology and Gene Therapy, Paul-Ehrlich-Institut, 63225 Langen, Germany; German Cancer Consortium, 69120 Heidelberg, Germany christian.buchholz@pei.de. ^[10]

主题词动物(Animals);骨髓(Bone Marrow);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);细胞系, 肿瘤(Cell Line, Tumor);细胞移植(Cell Transplantation);细胞, 培养的(Cells, Cultured);流式细胞术(Flow Cytometry);叉头转录因子类(Forkhead Transcription Factors);遗传载体(Genetic Vectors);绿色荧光蛋白质类(Green Fluorescent Proteins);HEK293细胞(HEK293 Cells);人类(Humans);免疫疗法, 过继(Immunotherapy, Adoptive);慢病毒属(Lentivirus);白细胞, 单核(Leukocytes, Mononuclear);萤光素酶类(Luciferases);小鼠, 近交NOD(Mice, Inbred NOD);小鼠, 基因敲除(Mice, Knockout);小鼠, SCID(Mice, SCID);脾(Spleen);胸腺(Thymus Gland);转导, 遗传(Transduction, Genetic);移植, 异种(Transplantation, Heterologous)

DOI 10.4049/jimmunol.1500956

PMID 26232436

发布时间 2015-08-22

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Exclusive Transduction of Human CD4+ T Cells upon Systemic Delivery of CD4-Targeted Lentiviral Vectors.

Journal of immunology (Baltimore, Md.

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Journal of immunology (Baltimore, Md.

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Exclusive Transduction of Human CD4+ T Cells upon Systemic Delivery of CD4-Targeted Lentiviral Vectors.

Journal of immunology (Baltimore, Md.

相似文献

Journal of immunology (Baltimore, Md.

相关期刊

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