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首页> Cancer letters> Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growth.

Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growth.

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作者： Laura D,Hover ^[1] ; Christian D,Young ^[2] ; Neil E,Bhola ^[2] ; Andrew J,Wilson ^[3] ; Dineo,Khabele ^[3] ; Charles C,Hong ^[4] ; Harold L,Moses ^[5] ; Philip,Owens ^[6]

作者单位： Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN, USA. ^[1] Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. ^[2] Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN, USA; Department of Obstetrics and Gynecology, Vanderbilt University, Nashville, TN, USA. ^[3] Research Medicine, Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN, USA; Department of Medicine, Cardiovascular, Vanderbilt University School of Medicine, Nashville, TN, USA. ^[4] Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, TN, USA. ^[5] Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: philip.owens@vanderbilt.edu. ^[6]

关键词 BMP BMPR1a DMH1 Ovarian cancer Platinum resistance

主题词抗肿瘤药(Antineoplastic Agents);骨形态发生蛋白受体(Bone Morphogenetic Protein Receptors);骨形态发生蛋白质类(Bone Morphogenetic Proteins);细胞增殖(Cell Proliferation);顺铂(Cisplatin);无病生存(Disease-Free Survival);抗药性, 肿瘤(Drug Resistance, Neoplasm);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);卵巢肿瘤(Ovarian Neoplasms);吡唑类(Pyrazoles);喹啉类(Quinolines);信号传导(Signal Transduction);球形体, 细胞(Spheroids, Cellular);肿瘤细胞, 培养的(Tumor Cells, Cultured)

DOI 10.1016/j.canlet.2015.07.032

PMID 26235139

发布时间 2021-10-20

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Cancer letters

Cancer letters

2015年368卷1期

79-87页

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