Is Thrombin Time useful for the assessment of dabigatran concentrations? An in vitro and ex vivo study.

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作者： Sarah,Lessire ^[1] ; Jonathan,Douxfils ^[2] ; Justine,Baudar ^[3] ; Nicolas,Bailly ^[3] ; Anne-Sophie,Dincq ^[4] ; Maximilien,Gourdin ^[4] ; Jean-Michel,Dogné ^[2] ; Bernard,Chatelain ^[3] ; François,Mullier ^[5]

作者单位： Department of Anesthesiology, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), CHU Dinant Godinne UcL Namur, Belgium; Department of Pharmacy, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, Belgium. ^[1] Department of Pharmacy, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, Belgium. ^[2] Hematology Laboratory, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), CHU Dinant Godinne UcL Namur, Belgium. ^[3] Department of Anesthesiology, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), CHU Dinant Godinne UcL Namur, Belgium. ^[4] Department of Pharmacy, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, Belgium; Hematology Laboratory, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), CHU Dinant Godinne UcL Namur, Belgium. Electronic address: mullierfrancois@gmail.com. ^[5]

关键词 Dabigatran Dabigatran etexilate Preoperative period Thrombin time Validation studies