Brain stem adenosine receptors modulate centrally mediated hypotensive responses in conscious rats: A review.
作者:
关键词
8-SPT, 8-(p-sulfophenyl)-theophylline. Non-selective adenosine receptor blockerA1, adenosine subtype A1 receptorA2A, adenosine subtype A2A receptorABC, avidin biotin complexABD rat, aortic barodenervated ratATP, adenosine triphosphateBP, blood pressureCGS21680, 2-[4-[(2-carboxyethyl)phenyl]ethylaminophenyl]ethylamino]-5′-N-ethylcarboxamidoadenosine. Selective A2A receptor agonistCNS, central nervous systemCPA, N6-cyclopentyladenosine. Selective A1 receptor agonistCentral adenosine receptorsCentrally mediated hypotensionClonidineConscious ratsDAG, diacylglycerolDPCPX, 8-cyclopentyl-1,3-dipropylxanthine. Selective A1 receptor antagonistERK1/2, extracellular signal regulated kinaseI.C., intracisternalI.V., intravenousI1, imidazoline subtype 1 receptorIP3, Inositol TriphosphateImidazoline I1-receptorJNK, C-Jun N-terminal kinaseL-NAME, Nω-nitro-l-arginine methyl ester hydrochloride. Non-selective nitric oxide synthase inhibitorMAPK-NOS signalingNO, nitric oxideNOS, nitric oxide synthaseNTS, nucleus tractus solitariusPC-PLC, phosphatidyl choline-selective phospholipase CPC12 cells, pheochromocytoma cellsPD98059, selective extracellular signal regulated kinase inhibitorPDE, phosphodiesterasePKA, protein kinase ARVLM, rostral ventrolateral medullaSAPK, stress activated protein kinaseSCH58261, 5-amino-7-(2-phenylethyl)-2-(2-furyl)-pyrazolo[4,3-[Formula: see text]]-1,2,4-triazolo[1,5-c]pyrimidine. Selective adenosine A2A antagonistSHR, spontaneously hypertensive ratSND, sympathetic neuronal dischargeSO, sham operated?=?conscious normotensive ratsWKY, Wistar Kyoto ratcAMP, cyclic adenosine monophosphateα2 AR, alpha 2 adrenergic receptorαMNE, alpha methyl norepinephrine
DOI
10.1016/j.jare.2014.12.005
PMID
26257930
发布时间
2020-09-29
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Journal of advanced research
2015年6卷3期
331-40页
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