A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer.

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作者： Chantel,Samardzija ^[1] ; Rodney B,Luwor ^[2] ; Mila,Volchek ^[3] ; Michael A,Quinn ^[4] ; Jock K,Findlay ^[1] ; Nuzhat,Ahmed ^[2]

作者单位： Women's Cancer Research Centre, Royal Women's Hospital, Victoria, 3052, Australia. ^[1] Department of Obstetrics and Gynaecology, University of Melbourne, Victoria, 3052, Australia. ^[2] Department of Surgery, University of Melbourne, Royal Melbourne Hospital, Victoria, 3052, Australia. ^[3] Department of Anatomical Pathology, Royal Women's Hospital, Victoria, 3052, Australia. ^[4] Hudson Institute of Medical Research, Victoria, 3168, Australia. ^[5] Women's Cancer Research Centre, Royal Women's Hospital, Victoria, 3052, Australia. nuzhata@unimelb.edu.au. ^[6] Department of Obstetrics and Gynaecology, University of Melbourne, Victoria, 3052, Australia. nuzhata@unimelb.edu.au. ^[7] Hudson Institute of Medical Research, Victoria, 3168, Australia. nuzhata@unimelb.edu.au. ^[8] Fiona Elsey Cancer Research Institute, Ballarat, Victoria, 3353, Australia. nuzhata@unimelb.edu.au. ^[9] Fiona Elsey Cancer Research Institute, 106-110 Lydiard Street South, Central Park, Ballarat, Victoria, 3363, Australia. nuzhata@unimelb.edu.au. ^[10]

主题词动物(Animals);抗原, 肿瘤(Antigens, Neoplasm);细胞黏附分子(Cell Adhesion Molecules);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);顺铂(Cisplatin);囊腺癌, 浆液(Cystadenocarcinoma, Serous);疾病模型, 动物(Disease Models, Animal);抗药性, 肿瘤(Drug Resistance, Neoplasm);女(雌)性(Female);基因表达(Gene Expression);基因敲低技术(Gene Knockdown Techniques);人类(Humans);小鼠(Mice);肿瘤转移(Neoplasm Metastasis);八聚体转录因子3(Octamer Transcription Factor-3);卵巢肿瘤(Ovarian Neoplasms);预后(Prognosis);RNA, 小分子干扰(RNA, Small Interfering);RNA结合蛋白质类(RNA-Binding Proteins);复发(Recurrence);SOXB1转录因子类(SOXB1 Transcription Factors);肿瘤负荷(Tumor Burden);肿瘤细胞, 培养的(Tumor Cells, Cultured)

DOI 10.1186/s12943-015-0417-y

PMID 26260289

发布时间 2021-03-15

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Molecular cancer

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A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer.

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A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer.

Molecular cancer

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Molecular cancer

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