The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain.

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作者： Mirjam,Steingruber ^[1] ; Eileen,Socher ^[2] ; Corina,Hutterer ^[3] ; Rike,Webel ^[4] ; Tim,Bergbrede ^[5] ; Tihana,Lenac ^[6] ; Heinrich,Sticht ^[7] ; Manfred,Marschall ^[8]

作者单位： Institute for Clinical and Molecular Virology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. mirjam.steingruber@viro.med.uni-erlangen.de. ^[1] Division of Bioinformatics, Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. eileen.socher@fau.de. ^[2] Institute for Clinical and Molecular Virology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. corina.hutterer@viro.med.uni-erlangen.de. ^[3] Institute for Clinical and Molecular Virology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. rike.webel@viro.med.uni-erlangen.de. ^[4] Lead Discovery Center GmbH, 44227 Dortmund, Germany. bergbrede@lead-discovery.de. ^[5] Department of Histology and Embryology, Faculty of Medicine, University of Rijeka, 51000 Rijeka, Croatia. tihana.lenac@medri.uniri.hr. ^[6] Division of Bioinformatics, Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. heinrich.sticht@fau.de. ^[7] Institute for Clinical and Molecular Virology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. manfred.marschall@viro.med.uni-erlangen.de. ^[8]

关键词 CDK ortholog active conformation cyclin B human cytomegalovirus kinase activity mode of kinase-cyclin interaction protein kinase pUL97 protein-protein interaction