Hyperbranched-hyperbranched polymeric nanoassembly to mediate controllable co-delivery of siRNA and drug for synergistic tumor therapy.
第一作者:
Hui-Zhen,Jia
第一单位:
Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan 430072, China.
作者:
关键词
2-(bromomethyl) phenylboronic acid (PubChem CID: 2773278)Acetic acid (PubChem CID: 176)Combinational therapyCore–corona nanostructureDiethyl carbonate (PubChem CID: 7766)Disodium hydrogen phosphate (PubChem CID: 24203)Doxorubicin (PubChem CID: 443939)Drug/siRNA co-deliveryHyperbranched polymerMethylene (PubChem CID: 6344)Polyethylenimine (PubChem CID: 9033)Potassium carbonate (PubChem CID: 11430)Sodium acetate (PubChem CID: 517045)Sodium dihydrogen phosphate (PubChem CID: 23672064)pH-sensitivity
主题词
动物(Animals);抗生素类, 抗肿瘤(Antibiotics, Antineoplastic);抗肿瘤药(Antineoplastic Agents);凋亡调节蛋白质类(Apoptosis Regulatory Proteins);自噬(Autophagy);细胞系, 肿瘤(Cell Line, Tumor);交联试剂(Cross-Linking Reagents);迟效制剂(Delayed-Action Preparations);多柔比星(Doxorubicin);药物释放系统(Drug Delivery Systems);药物协同作用(Drug Synergism);男(雄)性(Male);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);纳米结构(Nanostructures);肿瘤(Neoplasms);RNA干扰(RNA Interference);RNA, 小分子干扰(RNA, Small Interfering)
DOI
10.1016/j.jconrel.2015.08.006
PMID
26272764
发布时间
2016-11-25
- 浏览48
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文