Proteasome inhibitors prevent cell death and prolong survival of mice challenged by Shiga toxin.

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作者： Takayuki,Hattori ^[1] ; Miho,Watanabe-Takahashi ^[2] ; Nobumichi,Ohoka ^[1] ; Takashi,Hamabata ^[3] ; Koichi,Furukawa ^[4] ; Kiyotaka,Nishikawa ^[2] ; Mikihiko,Naito ^[1]

作者单位： Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, Tokyo 158-8501, Japan. ^[1] Faculty of Life and Medical Sciences, Doshisha University, Kyoto 610-0394, Japan. ^[2] Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan. ^[3] Department of Biochemistry II, Nagoya University Graduate School of Medicine, Nagoya 466-0065, Japan. ^[4]

关键词 Apoptosis Apoptosis inhibitory proteins BRZ, bortezomib CHX, cycloheximide ER, endoplasmic reticulum FLIP, FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein Mcl-1, myeloid cell leukemia 1 PARP, Poly(ADP-ribose) polymerase PI, propidium iodide Proteasome Proteasome inhibitor STEC, Shiga toxin-producing Escherichia coli Shiga toxin Stx, Shiga toxin c-IAP1, cellular inhibitor of apoptosis protein 1

DOI 10.1016/j.fob.2015.06.005

PMID 26273560

发布时间 2018-11-13

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Proteasome inhibitors prevent cell death and prolong survival of mice challenged by Shiga toxin.

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Proteasome inhibitors prevent cell death and prolong survival of mice challenged by Shiga toxin.

FEBS open bio

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FEBS open bio

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