首页> European journal of pharmacology> Effect of the potent and selective DP1 receptor antagonist, asapiprant (S-555739), in animal models of allergic rhinitis and allergic asthma.

Effect of the potent and selective DP1 receptor antagonist, asapiprant (S-555739), in animal models of allergic rhinitis and allergic asthma.

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第一作者： Go,Takahashi

第一单位： Discovery Research Laboratory for Innovative Frontier Medicines, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan.

作者： Go,Takahashi ^[1] ; Fujio,Asanuma ^[1] ; Noriko,Suzuki ^[2] ; Maki,Hattori ^[3] ; Shingo,Sakamoto ^[4] ; Akira,Kugimiya ^[2] ; Yasuhiko,Tomita ^[1] ; Goro,Kuwajima ^[5] ; William M,Abraham ^[6] ; Masashi,Deguchi ^[7] ; Akinori,Arimura ^[5] ; Michitaka,Shichijo ^[8]

作者单位： Discovery Research Laboratory for Innovative Frontier Medicines, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan. ^[1] Discovery Research Laboratory for Core Therapeutic Areas, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan. ^[2] Research Technology Services, Shionogi Techno Advance Research, Toyonaka, Osaka, Japan. ^[3] Research Laboratory for Development, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan. ^[4] Global Project Management, Shionogi & Co., Ltd., Osaka, Japan. ^[5] Department of Research, Mount Sinai Medical Center, Miami Beach, FL 33140, USA. ^[6] Strategic Research Planning Offices, Pharmaceutical Research Division, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan. ^[7] Discovery Research Laboratory for Innovative Frontier Medicines, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan. Electronic address: michitaka.shichijou@shionogi.co.jp. ^[8]

关键词 Allergic rhinitis Asapiprant Nasal congestion Prostaglandin D(2)Synthetic DP(1) receptor antagonist