piRNAs derived from ancient viral processed pseudogenes as transgenerational sequence-specific immune memory in mammals.

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第一作者： Nicholas F,Parrish

第一单位： Department of Viral Oncology, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan.

作者： Nicholas F,Parrish ^[1] ; Kan,Fujino ^[1] ; Yusuke,Shiromoto ^[2] ; Yuka W,Iwasaki ^[3] ; Hongseok,Ha ^[4] ; Jinchuan,Xing ^[4] ; Akiko,Makino ^[5] ; Satomi,Kuramochi-Miyagawa ^[2] ; Toru,Nakano ^[2] ; Haruhiko,Siomi ^[3] ; Tomoyuki,Honda ^[6] ; Keizo,Tomonaga ^[7]

作者单位： Department of Viral Oncology, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan. ^[1] Department of Pathology, Medical School and Graduate School of Frontier Biosciences, Osaka University, Osaka 565-0871, Japan. ^[2] Department of Molecular Biology, Keio University School of Medicine, Tokyo 160-8582, Japan. ^[3] Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA. ^[4] Department of Viral Oncology, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan Center for Emerging Virus Research, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan. ^[5] Department of Viral Oncology, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan Department of Tumor Viruses, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan. ^[6] Department of Viral Oncology, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan Department of Tumor Viruses, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan Department of Mammalian Regulatory Network, Graduate School of Biostudies, Kyoto University, Kyoto 606-8507, Japan. ^[7]

关键词 CRISPR/Cas endogenous viral elements paleovirology piRNA retrotransposon

主题词动物(Animals);免疫记忆(Immunologic Memory);哺乳动物(Mammals);灵长目(Primates);拟基因(Pseudogenes);RNA, 小分子干扰(RNA, Small Interfering);大鼠(Rats)

DOI 10.1261/rna.052092.115

PMID 26283688

发布时间 2018-11-13

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