首页> The Journal of neuroscience : the official journal of the Society for Neuroscience> Retinoic Acid-Mediated Regulation of GLI3 Enables Efficient Motoneuron Derivation from Human ESCs in the Absence of Extrinsic SHH Activation.

Retinoic Acid-Mediated Regulation of GLI3 Enables Efficient Motoneuron Derivation from Human ESCs in the Absence of Extrinsic SHH Activation.

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第一作者： Elizabeth L,Calder

第一单位： Center for Stem Cell Biology and Developmental Biology Program, Sloan-Kettering Institute, New York, New York 10065, Weill Graduate School of Medical Sciences of Cornell University, New York, New York 10065.

作者： Elizabeth L,Calder ^[1] ; Jason,Tchieu ^[2] ; Julius A,Steinbeck ^[3] ; Edmund,Tu ^[3] ; Sotirios,Keros ^[4] ; Shui-Wang,Ying ^[5] ; Manoj K,Jaiswal ^[5] ; Daniela,Cornacchia ^[3] ; Peter A,Goldstein ^[5] ; Viviane,Tabar ^[1] ; Lorenz,Studer ^[6]

作者单位： Center for Stem Cell Biology and Developmental Biology Program, Sloan-Kettering Institute, New York, New York 10065, Weill Graduate School of Medical Sciences of Cornell University, New York, New York 10065. ^[1] Center for Stem Cell Biology and Developmental Biology Program, Sloan-Kettering Institute, New York, New York 10065, studerl@mskcc.org tchieuj@mskcc.org. ^[2] Center for Stem Cell Biology and Developmental Biology Program, Sloan-Kettering Institute, New York, New York 10065. ^[3] Pediatrics, Weill Cornell Medical College, New York, New York 10065, and. ^[4] Departments of Anesthesiology and. ^[5] Center for Stem Cell Biology and Developmental Biology Program, Sloan-Kettering Institute, New York, New York 10065, Weill Graduate School of Medical Sciences of Cornell University, New York, New York 10065 studerl@mskcc.org tchieuj@mskcc.org. ^[6]

关键词 Gli3 SHH signaling directed differentiation motoneurons pluripotent stem cells retinoic acid