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Structure and Biophysical Properties of a Triple-Stranded Beta-Helix Comprising the Central Spike of Bacteriophage T4.

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第一作者： Sergey A,Buth

第一单位： Institute of Physics of Biological Systems, École Polytechnique Fédérale de Lausanne (EPFL), BSP 415, 1015 Lausanne, Switzerland. sergii.buth@epfl.ch.

作者： Sergey A,Buth ^[1] ; Laure,Menin ^[2] ; Mikhail M,Shneider ^[3] ; Jürgen,Engel ^[4] ; Sergei P,Boudko ^[5] ; Petr G,Leiman ^[6]

作者单位： Institute of Physics of Biological Systems, École Polytechnique Fédérale de Lausanne (EPFL), BSP 415, 1015 Lausanne, Switzerland. sergii.buth@epfl.ch. ^[1] Service de Spectrométrie de Masse, ISIC, EPFL, BCH 1520, 1015 Lausanne, Switzerland. laure.menin@epfl.ch. ^[2] Institute of Physics of Biological Systems, École Polytechnique Fédérale de Lausanne (EPFL), BSP 415, 1015 Lausanne, Switzerland. mm_shn@mail.ru.;Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Laboratory of Molecular Bioengineering, 16/10 Miklukho-Maklaya St., 117997 Moscow, Russia. mm_shn@mail.ru. ^[3] Department of Biophysical Chemistry, Biozentrum, University of Basel, Klingelbergstrasse 70, CH-4056 Basel, Switzerland. juergen.engel@unibas.ch. ^[4] Department of Biophysical Chemistry, Biozentrum, University of Basel, Klingelbergstrasse 70, CH-4056 Basel, Switzerland. spb@shcc.org.;Department of Biological Sciences, Purdue University, 915 W. State Street, West Lafayette, IN 47907-2054, USA. spb@shcc.org.;The Research Department, Shriner's Hospital for Children, 3101 Sam Jackson Park Road, Portland, OR 97239, USA. spb@shcc.org.;Department of Biochemistry and Molecular Biology, Oregon Health and Science University, 3181 Sam Jackson Park Road, Portland, OR 97239, USA. spb@shcc.org. ^[5] Institute of Physics of Biological Systems, École Polytechnique Fédérale de Lausanne (EPFL), BSP 415, 1015 Lausanne, Switzerland. petr.leiman@epfl.ch.;Department of Biological Sciences, Purdue University, 915 W. State Street, West Lafayette, IN 47907-2054, USA. petr.leiman@epfl.ch. ^[6]

关键词 X-ray crystallography amyloid-like structure fatty acid fibrous proteins intrinsic protein fluorescence low complexity amino acid sequence mass spectrometry protein folding protein stability β-helical proteins