JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis.

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第一作者： Hüseyin,Tuncay

第一单位： Institute-Associated Research Group 'Cell Adhesion and Cell Polarity', University of Münster, 48149 Münster, Germany.

作者： Hüseyin,Tuncay ^[1] ; Benjamin F,Brinkmann ^[2] ; Tim,Steinbacher ^[1] ; Annika,Schürmann ^[2] ; Volker,Gerke ^[3] ; Sandra,Iden ^[1] ; Klaus,Ebnet ^[2]

作者单位： Institute-Associated Research Group 'Cell Adhesion and Cell Polarity', University of Münster, 48149 Münster, Germany. ^[1] Institute of Medical Biochemistry, ZMBE, University of Münster, 48149 Münster, Germany. ^[2] Interdisciplinary Clinical Research Center (IZKF), University of Münster, 48149 Münster, Germany. ^[3] Cells-in-Motion Cluster of Excellence (EXC 1003-CiM), University of Münster, 48149 Münster, Germany. ^[4]

主题词肌动蛋白类(Actins);动物(Animals);细胞极性(Cell Polarity);狗(Dogs);动力蛋白(Dyneins);基因敲低技术(Gene Knockdown Techniques);HEK293细胞(HEK293 Cells);人类(Humans);显微镜检查, 荧光(Microscopy, Fluorescence);微管相关蛋白质类(Microtubule-Associated Proteins);有丝分裂(Mitosis);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);磷脂酰肌醇磷酸盐类(Phosphatidylinositol Phosphates);cdc42 GTP结合蛋白质(cdc42 GTP-Binding Protein)

DOI 10.1038/ncomms9128

PMID 26306570

发布时间 2018-11-13

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Nature communications

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JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis.

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JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis.

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