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Molecular Diagnostic Yield of Chromosomal Microarray Analysis and Whole-Exome Sequencing in Children With Autism Spectrum Disorder.

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作者单位: The Centre for Applied Genomics, Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada2Center of Neurodevelopmental Disorders (KIND), Pediatric Neuropsychiatry Unit, Department of Women's and Children's Health, K. [1] The Centre for Applied Genomics, Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada3Genome Diagnostics, Department of Pediatrics Laboratory Medicine, The Hospital for Sick Children, Toronto, Canada. [2] The Centre for Applied Genomics, Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada. [3] Autism Research Unit, The Hospital for Sick Children, Toronto, Ontario, Canada. [4] Department of Pediatrics and Genome Biology Program, The Hospital for Sick Children and Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. [5] Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada. [6] Department of Pediatrics, University of Alberta, Edmonton, Canada. [7] Bloorview Research Institute, Toronto, Ontario, Canada. [8] Provincial Medical Genetics Program, Eastern Health, St John's, Newfoundland and Labrador, Canada. [9] Child Health Program, Eastern Health, St John's, Newfoundland and Labrador, Canada13Discipline of Pediatrics, Memorial University of Newfoundland, St John's, Newfoundland and Labrador, Canada. [10] Child Health Program, Eastern Health, St John's, Newfoundland and Labrador, Canada. [11] Department of Pediatrics, Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, Ontario, Canada. [12] Centre for Addiction and Mental Health, The Hospital for Sick Children, University of Toronto, Toronto, Canada. [13] Disciplines of Genetics and Medicine, Memorial University of Newfoundland, St John's, Newfoundland and Labrador, Canada. [14] Genome Diagnostics, Department of Pediatrics Laboratory Medicine, The Hospital for Sick Children, Toronto, Canada15Cytogenetics Laboratory, Department of Pediatrics Laboratory Medicine, The Hospital for Sick Children, Toronto, Canada. [15] The Centre for Applied Genomics, Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada16Department of Molecular Genetics and the McLaughlin Centre, University of Toronto, Toronto, Canada. [16] Provincial Medical Genetics Program, Eastern Health, St John's, Newfoundland and Labrador, Canada14Disciplines of Genetics and Medicine, Memorial University of Newfoundland, St John's, Newfoundland and Labrador, Canada. [17]
DOI 10.1001/jama.2015.10078
PMID 26325558
发布时间 2022-03-11
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JAMA

JAMA

2015年314卷9期

895-903页

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