Pharmacokinetics in Drug Discovery: An Exposure-Centred Approach to Optimising and Predicting Drug Efficacy and Safety.

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作者： Andreas,Reichel ^[1] ; Philip,Lienau ^[2]

作者单位： Research Pharmacokinetics, Global Drug Discovery, Bayer Pharma, Berlin, Germany. andreas.reichel@bayer.com. ^[1] Research Pharmacokinetics, Global Drug Discovery, Bayer Pharma, Berlin, Germany. philip.lienau@bayer.com. ^[2]

关键词 ADME Candidate profiling Drug discovery Exposure Lead generation Lead optimisation PK/PD Pharmacokinetics Prediction

主题词动物(Animals);药物发现(Drug Discovery);药物评价, 临床前(Drug Evaluation, Preclinical);人类(Humans);模型, 生物学(Models, Biological);药代动力学(Pharmacokinetics)

DOI 10.1007/164_2015_26

PMID 26330260

发布时间 2016-03-31

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Handbook of experimental pharmacology

2016年232卷

235-60页

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Pharmacokinetics in Drug Discovery: An Exposure-Centred Approach to Optimising and Predicting Drug Efficacy and Safety.

Handbook of experimental pharmacology

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Pharmacokinetics in Drug Discovery: An Exposure-Centred Approach to Optimising and Predicting Drug Efficacy and Safety.

Handbook of experimental pharmacology

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Handbook of experimental pharmacology

相关期刊

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