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CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X.

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第一作者： Madina,Karimova

第一单位： Heinrich Pette Institute - Leibniz Institute for Experimental Virology, 20251 Hamburg, Germany.

作者： Madina,Karimova ^[1] ; Niklas,Beschorner ^[1] ; Werner,Dammermann ^[2] ; Jan,Chemnitz ^[1] ; Daniela,Indenbirken ^[1] ; Jan-Hendrik,Bockmann ^[2] ; Adam,Grundhoff ^[3] ; Stefan,Lüth ^[2] ; Frank,Buchholz ^[4] ; Julian,Schulze zur Wiesch ^[5] ; Joachim,Hauber ^[3]

作者单位： Heinrich Pette Institute - Leibniz Institute for Experimental Virology, 20251 Hamburg, Germany. ^[1] Department of Medicine I, University Medical Center Eppendorf, 20246 Hamburg, Germany. ^[2] Heinrich Pette Institute - Leibniz Institute for Experimental Virology, 20251 Hamburg, Germany.;German Center for Infection Research (DZIF), partner site Hamburg, Hamburg, Germany. ^[3] Department of Medical Systems Biology, University Hospital and Medical Faculty Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany. ^[4] Department of Medicine I, University Medical Center Eppendorf, 20246 Hamburg, Germany.;German Center for Infection Research (DZIF), partner site Hamburg, Hamburg, Germany. ^[5]

医学主题词脱氧核糖核酸酶Ⅰ(Deoxyribonuclease I);基因沉默(Gene Silencing);基因组, 病毒(Genome, Viral);乙型肝炎(Hepatitis B);乙型肝炎病毒(Hepatitis B virus);开放读码框架(Open Reading Frames)

DOI 10.1038/srep13734

PMID 26334116

发布时间 2024-01-04

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准确一般字义偏差语意偏离译文作用小提交