Inverse Agonist of Estrogen-Related Receptor γ Enhances Sodium Iodide Symporter Function Through Mitogen-Activated Protein Kinase Signaling in Anaplastic Thyroid Cancer Cells.

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第一作者： Thoudam Debraj,Singh

第一单位： Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.

作者： Thoudam Debraj,Singh ^[1] ; Shin Young,Jeong ^[1] ; Sang-Woo,Lee ^[1] ; Jeoung-Hee,Ha ^[2] ; In-Kyu,Lee ^[3] ; Seong Heon,Kim ^[4] ; Jina,Kim ^[4] ; Sung Jin,Cho ^[4] ; Byeong-Cheol,Ahn ^[1] ; Jaetae,Lee ^[5] ; Young Hyun,Jeon ^[6]

作者单位： Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu, Korea. ^[1] Department of Pharmacology, School of Medicine, Kyungpook National University, Daegu, Korea. ^[2] Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea. ^[3] New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Korea; and. ^[4] Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu, Korea New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Korea; and jeon9014@gmail.com jaetae@knu.ac.kr. ^[5] Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu, Korea Leading-Edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University Hospital, Daegu, Korea jeon9014@gmail.com jaetae@knu.ac.kr. ^[6]

关键词 MAP kinase signaling anaplastic thyroid cancer estrogen-related receptor gamma (ERRγ)radioiodide therapy sodium iodide symporter (NIS)