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Fetuin-A and risk of coronary heart disease: A Mendelian randomization analysis and a pooled analysis of AHSG genetic variants in 7 prospective studies.

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第一作者： Lars E,Laugsand

第一单位： Department of Public Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

作者： Lars E,Laugsand ^[1] ; Joachim H,Ix ^[2] ; Traci M,Bartz ^[3] ; Luc,Djousse ^[4] ; Jorge R,Kizer ^[5] ; Russell P,Tracy ^[6] ; Abbas,Dehghan ^[7] ; Kathryn,Rexrode ^[8] ; Oscar L,Lopez ^[9] ; Eric B,Rimm ^[10] ; David S,Siscovick ^[11] ; Christopher J,O'Donnell ^[12] ; Anne,Newman ^[13] ; Kenneth J,Mukamal ^[14] ; Majken K,Jensen ^[10]

作者单位： Department of Public Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA. ^[1] Nephrology Section, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA; Divisions of Nephrology and Preventive Medicine, University of California San Diego, San Diego, CA, USA. ^[2] Department of Biostatistics, University of Washington, Seattle, WA, USA. ^[3] Boston Veterans Affairs Healthcare System, Boston, MA, USA; Division of Aging, Brigham and Women's Hospital, Boston, MA, USA. ^[4] Department of Medicine, and Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, NY, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. ^[5] Department of Pathology and Biochemistry, University of Vermont College of Medicine, Burlington, USA. ^[6] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands. ^[7] Division of Aging, Brigham and Women's Hospital, Boston, MA, USA. ^[8] Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA. ^[9] Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. ^[10] Cardiovascular Health Research Unit, Department of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, WA, USA; Group Health Research Institute, Group Health Cooperative, Seattle, WA, USA. ^[11] National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA; Division of Intramural Research, National Heart, Lung and Blood Institute, Bethesda, MD, USA; Cardiology Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. ^[12] UPMC/University of Pittsburgh Schools of the Health Sciences, Pittsburgh, PA, USA. ^[13] Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA. ^[14]

关键词 Coronary heart disease Fetuin-A Mendelian randomization Meta-analysis Single nucleotide polymorphisms