Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.

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作者： Tui,Neri ^[1] ; Sharon,Muggeo ^[1] ; Marianna,Paulis ^[1] ; Maria Elena,Caldana ^[1] ; Laura,Crisafulli ^[1] ; Dario,Strina ^[1] ; Maria Luisa,Focarelli ^[1] ; Francesca,Faggioli ^[1] ; Camilla,Recordati ^[2] ; Samantha,Scaramuzza ^[1] ; Eugenio,Scanziani ^[3] ; Stefano,Mantero ^[1] ; Chiara,Buracchi ^[4] ; Cristina,Sobacchi ^[1] ; Angelo,Lombardo ^[5] ; Luigi,Naldini ^[5] ; Paolo,Vezzoni ^[1] ; Anna,Villa ^[6] ; Francesca,Ficara ^[1]

作者单位： Milan Unit, Istituto di Ricerca Genetica e Biomedica, CNR, 20138 Milan, Italy; Humanitas Clinical and Research Center, via Manzoni 56, 20089 Rozzano (Mi), Italy. ^[1] Mouse & Animal Pathology Laboratory, Fondazione Filarete, 20139 Milano, Italy. ^[2] Mouse & Animal Pathology Laboratory, Fondazione Filarete, 20139 Milano, Italy; Department of Veterinary Sciences and Public Health, University of Milan, Via Celoria 10, 20133 Milan, Italy. ^[3] Humanitas Clinical and Research Center, via Manzoni 56, 20089 Rozzano (Mi), Italy. ^[4] San Raffaele Telethon Institute for Gene Therapy (TIGET), San Raffaele Scientific Institute and Vita Salute San Raffaele University, 20132 Milan, Italy. ^[5] Milan Unit, Istituto di Ricerca Genetica e Biomedica, CNR, 20138 Milan, Italy; Humanitas Clinical and Research Center, via Manzoni 56, 20089 Rozzano (Mi), Italy. Electronic address: anna.villa@humanitasresearch.it. ^[6]

主题词动物(Animals);细胞分化(Cell Differentiation);细胞系(Cell Line);血细胞生成(Hematopoiesis);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);突变(Mutation);髓系细胞(Myeloid Cells);破骨细胞(Osteoclasts);骨硬化症(Osteopetrosis);靶基因修复(Targeted Gene Repair);空泡质子转运ATP酶(Vacuolar Proton-Translocating ATPases)

DOI 10.1016/j.stemcr.2015.08.005

PMID 26344905

发布时间 2022-01-29

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Stem cell reports

2015年5卷4期

558-68页

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Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.

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Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.

Stem cell reports

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Stem cell reports

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