The Histone Deacetylase Inhibitor Vaproic Acid Induces Cell Growth Arrest in Hepatocellular Carcinoma Cells via Suppressing Notch Signaling.

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作者： Guangchun,Sun ^[1] ; Lily V,Mackey ^[2] ; David H,Coy ^[2] ; Cui-Yun,Yu ^[3] ; Lichun,Sun ^[4]

作者单位： 1. Department of Pharmacy, The Fifth People's Hospital of Shanghai, Fudan University; 801 He-Qing Rd., Shanghai 200240, China. ^[1] 3. Department of Medicine, School of Medicine, Tulane Health Sciences Center, New Orleans, LA 70112-2699, USA. ^[2] 2. Institute of Pharmacy & Pharmacology, Department of Pharmacy, University of South China, Hengyang 421001, China ; 3. Department of Medicine, School of Medicine, Tulane Health Sciences Center, New Orleans, LA 70112-2699, USA. ^[3] 1. Department of Pharmacy, The Fifth People's Hospital of Shanghai, Fudan University; 801 He-Qing Rd., Shanghai 200240, China ; 2. Institute of Pharmacy & Pharmacology, Department of Pharmacy, University of South China, Hengyang 421001, China ; 3. Department of Medicine, School of Medicine, Tulane Health Sciences Center, New Orleans, LA 70112-2699, USA. ^[4]

关键词 HDAC inhibitor Notch signaling hepatocellular carcinoma receptor-targeting.valproic acid

DOI 10.7150/jca.12135

PMID 26366213

发布时间 2022-04-10

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