Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody.
第一作者:
Tianlei,Ying
第一单位:
Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, Shanghai Medical College, Fudan University, Shanghai 200032, China.
作者:
医学主题词
等位基因(Alleles);抗体, 中和(Antibodies, Neutralizing);抗体, 病毒(Antibodies, Viral);结晶(Crystallization);结晶学, X线(Crystallography, X-Ray);表位(Epitopes);基因, 免疫球蛋白重链(Genes, Immunoglobulin Heavy Chain);人类(Humans);免疫球蛋白G(Immunoglobulin G);体细胞高突变, 免疫球蛋白(Somatic Hypermutation, Immunoglobulin)
DOI
10.1038/ncomms9223
PMID
26370782
发布时间
2022-04-08
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Nature communications
8223页
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