NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity.
第一作者:
Kimberley J,Anderson
第一单位:
Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Faculty of Health, Deakin University, Melbourne, Australia.
作者:
关键词
Acta1, skeletal muscle alpha-actinAkt, thymoma viral proto-oncogeneApoptosisBax, Bcl-2-associated X proteinBcl-2, B cell leukemia/lymphoma 2Bcl-xL, Bcl-2-like 1Caspase, apoptosis-related cysteine peptidaseCdk, cyclin-dependent kinaseCkm, muscle creatine kinaseDifferentiationER stressER, endoplasmic reticulumGRP78, glucose-regulated protein 78H2O2, hydrogen peroxideLipotoxicityMRFs, myogenic regulatory factorsMcl-1, myeloid cell leukemia 1Myf5, myogenic factor 5Myh7, myosin, heavy polypeptide 7MyoD, myogenic differentiationMyoblastMyotubeNDRG2NDRG2, N-myc downstream-regulated gene 2Oxidative stressPA, palmitatePARP, poly (ADP-ribose) polymerase family, memberPKCθ, protein kinase C thetaProliferationRb, retinoblastomaSGK1, serum- and glucocorticoid-inducible kinase 1p21, p21 waf1/cip1p27, p27 kip1
DOI
10.1016/j.fob.2015.08.001
PMID
26380811
发布时间
2018-11-13
- 浏览15
FEBS open bio
668-81页
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