The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium.
作者:
Neil M,Davies [1]
;
Tom R,Gaunt [2]
;
Sarah J,Lewis [3]
;
Jeff,Holly [4]
;
Jenny L,Donovan [3]
;
Freddie C,Hamdy [4]
;
John P,Kemp [5]
;
Rosalind,Eeles [3]
;
Doug,Easton [6]
;
Zsofia,Kote-Jarai [4]
;
Ali Amin,Al Olama [7]
;
Sara,Benlloch [8]
;
Kenneth,Muir [9]
;
Graham G,Giles [10]
;
Fredrik,Wiklund [8]
;
Henrik,Gronberg [10]
;
Christopher A,Haiman [10]
;
Johanna,Schleutker [11]
;
Børge G,Nordestgaard [12]
;
Ruth C,Travis [13]
;
David,Neal [14]
;
Nora,Pashayan [14]
;
Kay-Tee,Khaw [15]
;
Janet L,Stanford [16]
;
William J,Blot [17]
;
Stephen,Thibodeau [18]
;
Christiane,Maier [19]
;
Adam S,Kibel [20]
;
Cezary,Cybulski [21]
;
Lisa,Cannon-Albright [22]
;
Hermann,Brenner [23]
;
Jong,Park [24]
;
Radka,Kaneva [25]
;
Jyotsna,Batra [26]
;
Manuel R,Teixeira [27]
;
Hardev,Pandha [28]
;
PRACTICAL consortium [29]
;
Mark,Lathrop [30]
;
George Davey,Smith [31]
;
Richard M,Martin [32]
作者单位:
School of Social and Community Medicine, University of Bristol, Bristol, UK. neil.davies@bristol.ac.uk.
[1]
MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. neil.davies@bristol.ac.uk.
[2]
School of Social and Community Medicine, University of Bristol, Bristol, UK.
[3]
MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
[4]
School of Clinical Sciences, University of Bristol, Bristol, BS10 5NB, UK.
[5]
Nuffield Department of Surgery, University of Oxford, Oxford, UK.
[6]
University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD, Australia.
[7]
The Institute of Cancer Research, London, SM2 5NG, UK.
[8]
The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.
[9]
Strangeways Laboratory, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Worts Causeway, Cambridge, UK.
[10]
Institute of Population Health, University of Manchester, Manchester, UK.
[11]
Cancer Epidemiology Centre, The Cancer Council Victoria, 615 St Kilda Road, Melbourne, VIC, Australia.
[12]
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.
[13]
Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
[14]
Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, CA, USA.
[15]
Department of Medical Biochemistry and Genetics, University of Turku, Turku, Finland.
[16]
Institute of Biomedical Technology/BioMediTech, University of Tampere and FimLab Laboratories, Tampere, Finland.
[17]
Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev Ringvej 75, 2730, Herlev, Denmark.
[18]
Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
[19]
Surgical Oncology (Uro-Oncology: S4), University of Cambridge, Addenbrooke's Hospital, Hills Road, Box 279, Cambridge, UK.
[20]
Li Ka Shing Centre, Cancer Research UK Cambridge Research Institute, Cambridge, UK.
[21]
Strangeways Laboratory, Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Worts Causeway, Cambridge, UK.
[22]
Department of Applied Health Research, University College London, 1-19 Torrington Place, London, WC1E 7HB, UK.
[23]
Cambridge Institute of Public Health, University of Cambridge, Forvie Site, Robinson Way, Cambridge, CB2 0SR, UK.
[24]
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
[25]
Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA.
[26]
International Epidemiology Institute, 1455 Research Blvd., Suite 550, Rockville, MD, 20850, USA.
[27]
Mayo Clinic, Rochester, MN, USA.
[28]
Department of Urology, University Hospital Ulm, Ulm, Germany.
[29]
Institute of Human Genetics, University Hospital Ulm, Ulm, Germany.
[30]
Brigham and Women's Hospital/Dana-Farber Cancer Institute, 45 Francis Street-ASB II-3, Boston, MA, 02115, USA.
[31]
Washington University, St. Louis, Missouri.
[32]
International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
[33]
Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.
[34]
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[35]
Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[36]
German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[37]
Division of Cancer Prevention and Control, H. Lee Moffitt Cancer Center, 12902 Magnolia Dr., Tampa, FL, USA.
[38]
Molecular Medicine Center and Department of Medical Chemistry and Biochemistry, Medical University Sofia, 2 Zdrave St, 1431, Sofia, Bulgaria.
[39]
Australian Prostate Cancer Research Centre-Qld, Institute of Health and Biomedical Innovation and School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.
[40]
Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.
[41]
Biomedical Sciences Institute (ICBAS), Porto University, Porto, Portugal.
[42]
The University of Surrey, Guildford, Surrey, GU2 7XH, UK.
[43]
Commissariat à l'Energie Atomique, Center National de Génotypage, Evry, France.
[44]
McGill University-Génome Québec Innovation Centre, Montreal, Canada.
[45]
School of Social and Community Medicine, University of Bristol, Bristol, UK. richard.martin@bristol.ac.uk.
[46]
MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. richard.martin@bristol.ac.uk.
[47]
Bristol Nutrition Biomedical Research Unit, National Institute for Health Research, Bristol, UK. richard.martin@bristol.ac.uk.
[48]
主题词
体脂肪率(Adiposity);老年人(Aged);等位基因(Alleles);身高(Body Height);人体质量指数(Body Mass Index);病例对照研究(Case-Control Studies);遗传变异(Genetic Variation);基因型(Genotype);人类(Humans);发病率(Incidence);男(雄)性(Male);孟德尔随机化分析(Mendelian Randomization Analysis);中年人(Middle Aged);肥胖症(Obesity);表型(Phenotype);多态性, 单核苷酸(Polymorphism, Single Nucleotide);前列腺肿瘤(Prostatic Neoplasms);危险因素(Risk Factors)
DOI
10.1007/s10552-015-0654-9
PMID
26387087
发布时间
2024-04-03
- 浏览66

Cancer causes & control
Cancer causes & control
1603-16页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文