Conditional Ablation of Retinol Dehydrogenase 10 in the Retinal Pigmented Epithelium Causes Delayed Dark Adaption in Mice.

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第一作者： Bhubanananda,Sahu

第一单位： Departments of Ophthalmology and Visual Sciences, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106.

作者： Bhubanananda,Sahu ^[1] ; Wenyu,Sun ^[2] ; Lindsay,Perusek ^[1] ; Vipulkumar,Parmar ^[1] ; Yun-Zheng,Le ^[3] ; Michael D,Griswold ^[4] ; Krzysztof,Palczewski ^[5] ; Akiko,Maeda ^[6]

作者单位： Departments of Ophthalmology and Visual Sciences, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106. ^[1] Polgenix, Inc., Cleveland, Ohio 44106. ^[2] Departments of Medicine Endocrinology, Cell Biology, and Ophthalmology and the Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104. ^[3] School of Molecular Biosciences, Washington State University, Pullman, Washington 99164. ^[4] Departments of Pharmacology, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106; Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106. ^[5] Departments of Ophthalmology and Visual Sciences, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106; Departments of Pharmacology, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106. Electronic address: aam19@case.edu. ^[6]

关键词 RDH10 RDH11 RDH5 dark adaption dehydrogenase retina retinal degeneration retinal pigmented epithelium retinoid retinol retinol dehydrogenase vision