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Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.

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作者: Tae-Hwi,Schwantes-An [1] ; Juan,Zhang [2] ; Li-Shiun,Chen [1] ; Sarah M,Hartz [3] ; Robert C,Culverhouse [4] ; Xiangning,Chen [4] ; Hilary,Coon [5] ; Josef,Frank [6] ; Helen M,Kamens [7] ; Bettina,Konte [8] ; Leena,Kovanen [9] ; Antti,Latvala [10] ; Lisa N,Legrand [11] ; Brion S,Maher [12] ; Whitney E,Melroy [13] ; Elliot C,Nelson [14] ; Mark W,Reid [15] ; Jason D,Robinson [16] ; Pei-Hong,Shen [9] ; Bao-Zhu,Yang [10] ; Judy A,Andrews [4] ; Paul,Aveyard [17] ; Olga,Beltcheva [18] ; Sandra A,Brown [19] ; Dale S,Cannon [20] ; Sven,Cichon [17] ; Robin P,Corley [21] ; Norbert,Dahmen [22] ; Louisa,Degenhardt [23] ; Tatiana,Foroud [7] ; Wolfgang,Gaebel [24] ; Ina,Giegling [25] ; Stephen J,Glatt [9] ; Richard A,Grucza [26] ; Jill,Hardin [27] ; Annette M,Hartmann [28] ; Andrew C,Heath [29] ; Stefan,Herms [30] ; Colin A,Hodgkinson [12] ; Per,Hoffmann [31] ; Hyman,Hops [4] ; David,Huizinga [32] ; Marcus,Ising [12] ; Eric O,Johnson [4] ; Elaine,Johnstone [24] ; Radka P,Kaneva [25] ; Kenneth S,Kendler [19] ; Falk,Kiefer [24] ; Henry R,Kranzler [25] ; Ken S,Krauter [17] ; Orna,Levran [33] ; Susanne,Lucae [34] ; Michael T,Lynskey [35] ; Wolfgang,Maier [36] ; Karl,Mann [22] ; Nicholas G,Martin [6] ; Manuel,Mattheisen [37] ; Grant W,Montgomery [38] ; Bertram,Müller-Myhsok [9] ; Michael F,Murphy [39] ; Michael C,Neale [40] ; Momchil A,Nikolov [34] ; Denise,Nishita [41] ; Markus M,Nöthen [42] ; John,Nurnberger [43] ; Timo,Partonen [44] ; Michele L,Pergadia [24] ; Maureen,Reynolds [45] ; Monika,Ridinger [46] ; Richard J,Rose [44] ; Noora,Rouvinen-Lagerström [34] ; Norbert,Scherbaum [47] ; Christine,Schmäl [6] ; Michael,Soyka [4] ; Michael C,Stallings [22] ; Michael,Steffens [32] ; Jens,Treutlein [24] ; Ming,Tsuang [48] ; Tamara L,Wall [13] ; Norbert,Wodarz [4] ; Vadim,Yuferov [49] ; Peter,Zill [50] ; Andrew W,Bergen [51] ; Jingchun,Chen [52] ; Paul M,Cinciripini [13] ; Howard J,Edenberg [53] ; Marissa A,Ehringer [43] ; Robert E,Ferrell [54] ; Joel,Gelernter [55] ; David,Goldman [9] ; John K,Hewitt [56] ; Christian J,Hopfer [57] ; William G,Iacono [8] ; Jaakko,Kaprio [23] ; Mary Jeanne,Kreek [23] ; Ivo M,Kremensky [50] ; Pamela A F,Madden [40] ; Matt,McGue [58] ; Marcus R,Munafò [32] ; Robert A,Philibert [6] ; Marcella,Rietschel [18] ; Alec,Roy [59] ; Dan,Rujescu [9] ; Sirkku T,Saarikoski [10] ; Gary E,Swan [60] ; Alexandre A,Todorov [20] ; Michael M,Vanyukov [61] ; Robert B,Weiss [62] ; Laura J,Bierut [19] ; Nancy L,Saccone [9]
作者单位: Department of Genetics, Washington University School of Medicine, 4523 Clayton Avenue, Campus Box 8232, St. Louis, MO, 63110, USA. [1] Genometrics Section, Computational and Statistical Genomics Branch, Division of Intramural Research, National Human Genome Research Institute, US National Institutes of Health (NIH), Baltimore, MD, 21224, USA. [2] Key Laboratory of Brain Function and Disease, School of Life Sciences, Chinese Academy of Sciences, University of Science and Technology of China, Hefei, Anhui, 230026, China. [3] Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, 63110, USA. [4] Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, 63110, USA. [5] Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, 23298, USA. [6] Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT, 84108, USA. [7] Department of Genetic Epidemiology in Psychiatry, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, 68159, Mannheim, Germany. [8] Institute for Behavioral Genetics, University of Colorado, Boulder, CO, 80309, USA. [9] Department of Integrative Physiology, University of Colorado, Boulder, CO, 80309, USA. [10] Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA, 16802, USA. [11] Department of Psychiatry, Universitätsklinikum Halle (Saale), 06112, Halle (Saale), Germany. [12] Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, 00271, Finland. [13] Department of Public Health, University of Helsinki, Helsinki, 00014, Finland. [14] Department of Psychology, University of Minnesota, Minneapolis, MN, 55455, USA. [15] Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, 21205, USA. [16] Oregon Research Institute, Eugene, OR, 97403, USA. [17] Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. [18] Section of Human Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, 20892, USA. [19] Department of Psychiatry, Yale University, New Haven, CT, 06516, USA. [20] Department of Primary Care Health Sciences, University of Oxford, Oxford, OX2 6GG, United Kingdom. [21] Department of Medical Chemistry and Biochemistry, Molecular Medicine Center, Medical University-Sofia, 1431, Sofia, Bulgaria. [22] Department of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA. [23] Department. of Genomics, Life and Brain Center, Institute of Human Genetics, University of Bonn, Bonn, 53127, Germany. [24] Division of Medical Genetics, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, 4003, Switzerland. [25] Ökumenisches Hainich-Klinikum, Mühlhausen/Thüringen, Germany. [26] National Drug and Alcohol Research Centre, University of New South Wales, Randwick, NSW, 2031, Australia. [27] School of Population and Global Health, University of Melbourne, Melbourne, 3010, Australia. [28] Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. [29] University of Düsseldorf, 40225, Düsseldorf, Germany. [30] Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, 13210, USA. [31] Center for Health Sciences, Biosciences Division, SRI International, Menlo Park, CA, 94025, USA. [32] Institute of Behavioral Science, University of Colorado, Boulder, CO, 80309, USA. [33] Max-Planck-Institute of Psychiatry, 80804, Munich, Germany. [34] Behavioral Health Research Division, Research Triangle Institute International, Durham, NC, 27709, USA. [35] Department of Oncology, University of Oxford, Oxford, OX3 7DQ, United Kingdom. [36] Department of Addictive Behavior and Addiction Medicine, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, 68159, Mannheim, Germany. [37] Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. [38] Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO, 80309, USA. [39] Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, 10065, USA. [40] Addictions Department, Institute of Psychiatry, King's College London, London, SE5 8BB, UK. [41] University of Bonn, 53113, Bonn, Germany. [42] Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, 68159, Mannheim, Germany. [43] Department of Genetic Epidemiology, Queensland Institute of Medical Research, Brisbane, QLD, 4029, Australia. [44] Harvard School of Public Health, Boston, MA, 02115, USA. [45] Aarhus University, Aarhus, 8000, Denmark. [46] Childhood Cancer Research Group, University of Oxford, Oxford, OX3 7LG, UK. [47] Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. [48] Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, 15213, USA. [49] Department of Psychiatry, University Medical Center Regensburg, University of Regensburg, 8548, Regensburg, Germany. [50] Psychiatric Hospital, Konigsfelden, Windisch, Switzerland. [51] Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, 47405, USA. [52] Addiction Research Group at the Department of Psychiatry and Psychotherapy, LVR Hospital Essen, University of Duisburg-Essen, 45147, Essen, Germany. [53] Department of Psychiatry, University of Munich, 3860, Munich, Germany. [54] Private Hospital Meiringen, Meiringen, Switzerland. [55] Department of Psychology & Neuroscience, University of Colorado, Boulder, CO, 80309, USA. [56] Research Department, Federal Institute for Drugs and Medical Devices (BfArM), Kurt-Georg-Kiesinger-Allee 3, 53175, Bonn, Germany. [57] University of Munich, Munich, Germany. [58] Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. [59] Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, 15261, USA. [60] Department of Genetics, Yale University, New Haven, CT, 06516, USA. [61] Department of Neurobiology, Yale University, New Haven, CT, 06516, USA. [62] Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA. [63] Institute for Molecular Medicine FIMM, University of Helsinki, 00014, Helsinki, Finland. [64] MRC Integrative Epidemiology Unit, UK Centre for Tobacco and Alcohol Studies, and School of Experimental Psychology, University of Bristol, Bristol, BS8 1TU, UK. [65] Department of Psychiatry, University of Iowa, Iowa City, IA, 52242, USA. [66] Psychiatry Service, Department of Veteran Affairs, New Jersey VA Health Care System, East Orange, NJ, 07018, USA. [67] Department of Medicine, Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA, 94304, USA. [68] Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, 84112, USA. [69] Department of Genetics, Washington University School of Medicine, 4523 Clayton Avenue, Campus Box 8232, St. Louis, MO, 63110, USA. nlims@genetics.wustl.edu. [70]
DOI 10.1007/s10519-015-9737-3
PMID 26392368
发布时间 2024-06-15
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