In situ biomarker discovery and label-free molecular histopathological diagnosis of lung cancer by ambient mass spectrometry imaging.

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作者： Tiegang,Li ^[1] ; Jiuming,He ^[1] ; Xinxin,Mao ^[2] ; Ying,Bi ^[3] ; Zhigang,Luo ^[1] ; Chengan,Guo ^[3] ; Fei,Tang ^[3] ; Xin,Xu ^[4] ; Xiaohao,Wang ^[3] ; Mingrong,Wang ^[4] ; Jie,Chen ^[2] ; Zeper,Abliz ^[1]

作者单位： State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P. R. China. ^[1] Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, P. R. China. ^[2] State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instruments, Tsinghua University, Beijing 100084, P. R. China. ^[3] State Key Laboratory of Molecular Oncology, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, P. R. China. ^[4]

主题词人类(Humans);免疫组织化学(Immunohistochemistry);肺肿瘤(Lung Neoplasms);质谱分析法(Mass Spectrometry);代谢组(Metabolome);代谢组学(Metabolomics);显微镜检查, 荧光(Microscopy, Fluorescence);敏感性与特异性(Sensitivity and Specificity)

DOI 10.1038/srep14089

PMID 26404114

发布时间 2024-03-23

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In situ biomarker discovery and label-free molecular histopathological diagnosis of lung cancer by ambient mass spectrometry imaging.

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In situ biomarker discovery and label-free molecular histopathological diagnosis of lung cancer by ambient mass spectrometry imaging.

Scientific reports

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