Motor onset and diagnosis in Huntington disease using the diagnostic confidence level.

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第一作者： Dawei,Liu

第一单位： Department of Psychiatry, Carver College of Medicine, The University of Iowa, 200 Hawkins Drive, Iowa City, IA, 52242, USA.

作者： Dawei,Liu ^[1] ; Jeffrey D,Long ^[2] ; Ying,Zhang ^[1] ; Lynn A,Raymond ^[3] ; Karen,Marder ^[4] ; Anne,Rosser ^[5] ; Elizabeth A,McCusker ^[6] ; James A,Mills ^[7] ; Jane S,Paulsen ^[8] ; PREDICT-HD Investigators and Coordinators of the Huntington Study Group ^[9]

作者单位： Department of Psychiatry, Carver College of Medicine, The University of Iowa, 200 Hawkins Drive, Iowa City, IA, 52242, USA. ^[1] Biogen, 300 Binney Street, Cambridge, MA, 02142, USA. ^[2] Department of Biostatistics, College of Public Health, The University of Iowa, S160 CPHB, 145 N. Riverside Drive, Iowa City, IA, 52242, USA. ^[3] Department of Biostatistics, Indiana University Fairbanks School of Public Health, 410 W. Tenth Street, Suite 3000, Indianapolis, IN, 46202, USA. ^[4] Department of Psychiatry and Brain Research Centre, University of British Columbia, Detwiller Pavilion, 2255 Wesbrook Mall, Vancouver, BC, V6T 2A1, Canada. ^[5] Department of Neurology, Gertrude H. Sergievsky Center, Taub Institute on Alzheimers Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, 710 West 168th Street, New York, NY, 10032, USA. ^[6] Department of Psychiatry, Columbia University Medical Center, 622 West 168th Street, New York, NY, 10032, USA. ^[7] Institute for Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Hadyn Ellis Building, Maindy Road, Cathays, Cardiff, CF24 4HQ, UK. ^[8] School of Biosciences, Cardiff University, The Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX, UK. ^[9] Department of Neurology, Westmead Hospital, The University of Sydney, Cnr Hawkesbury and Darcy Roads, Westmead, NSW, 2145, Australia. ^[10] Department of Psychiatry, Carver College of Medicine, The University of Iowa, 200 Hawkins Drive, Iowa City, IA, 52242, USA. predict-publications@uiowa.edu. ^[11] Department of Neurology, Carver College of Medicine, The University of Iowa, 2007 Roy Carver Pavilion, 200 Hawkins Drive, Iowa City, IA, 52242, USA. predict-publications@uiowa.edu. ^[12] Department of Psychology, The University of Iowa, E11 Seashore Hall, Iowa City, IA, 52242, USA. predict-publications@uiowa.edu. ^[13]

关键词 Diagnosis Diagnostic confidence level Hidden Markov model Huntington disease Onset Prediction