Wedelolactone protects human bronchial epithelial cell injury against cigarette smoke extract-induced oxidant stress and inflammation responses through Nrf2 pathway.

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作者： Shumin,Ding ^[1] ; Xuefeng,Hou ^[2] ; Jiarui,Yuan ^[3] ; Xiaobin,Tan ^[4] ; Juan,Chen ^[3] ; Nan,Yang ^[3] ; Yi,Luo ^[5] ; Ziyu,Jiang ^[5] ; Ping,Jin ^[4] ; Zibo,Dong ^[6] ; Liang,Feng ^[7] ; Xiaobin,Jia ^[8]

作者单位： Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing, Jiangsu 210028, PR China; School of Pharmaceutial Engineering and Life Science, Changzhou University, Changzhou, Jiangsu 213164, PR China. ^[1] Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing, Jiangsu 210028, PR China; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui 230012, PR China. ^[2] Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing, Jiangsu 210028, PR China; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 230012, PR China. ^[3] Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing, Jiangsu 210028, PR China. ^[4] Department of Oncology, Jiangsu Provincial Academy of Chinese Medicine, Nanjing, Jiangsu 210028, PR China. ^[5] School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 230012, PR China; Jumpcan Pharmaceutical Co., Ltd., Taixing 225400, PR China. Electronic address: 13961098521@163.com. ^[6] Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing, Jiangsu 210028, PR China. Electronic address: wenmoxiushi@163.com. ^[7] Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing, Jiangsu 210028, PR China. Electronic address: jxiaobin2005@hotmail.com. ^[8]

关键词 Antioxidant Chemoprevention Cigarette smoke Inflammatory Lung cancer Wedelolactone